Sabatowski Rainer, Kaiser Ulrike, Gossrau Gudrun
UniversitätsSchmerzCentrum, Universitätsklinikum Carl Gustav Carus, Technische Universität Dresden.
Anasthesiol Intensivmed Notfallmed Schmerzther. 2010 Jun;45(6):384-5. doi: 10.1055/s-0030-1255344. Epub 2010 Jun 10.
Opioids are important in pain management of patients suffering from chronic pain. However, opioid use is associated with several concerns, such as opioid induced impairment of cognitive and psychomotor performance. Several studies could demonstrate that opioid treatment in stable doses does not necessarily impair complex activities such as driving ability. But due to intraindividual variability to opioid response and other confounding factors (e.g. pain intensity, co-morbidity) judgements have to be made on an individual basis only.
阿片类药物在慢性疼痛患者的疼痛管理中很重要。然而,使用阿片类药物存在一些问题,比如阿片类药物会导致认知和精神运动能力受损。多项研究表明,稳定剂量的阿片类药物治疗不一定会损害驾驶能力等复杂活动。但由于个体对阿片类药物反应的差异以及其他混杂因素(如疼痛强度、合并症),只能基于个体情况进行判断。