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[阿片类药物与驾驶]

[Opioids and driving].

作者信息

Semionov Valentina, Shvartzman Pesach

机构信息

Pain and Palliative Care Unit, Siaal Research Center for Family Medicine and Primary Care, Ben-Gurion University of the Negev.

出版信息

Harefuah. 2011 Dec;150(12):922-5, 934.

PMID:22352287
Abstract

In many European countries the use of opioids for long-term treatment of non-malignant pain has dramatically increased during the last decade in order to improve the patient's quality of life, to allow social activities and the return to work. Therefore, the issue of driving by patients regularly taking opioids, and its medico-legal aspects, concerns physicians, patients and society. Many studies explored the effect of opioids drugs on cognitive and driving skills using healthy subjects, patients taking opioids for chronic malignant and non-malignant pain, with different administration methods and in combination with other psycho-active drugs. These studies show that the patients taking stable dosages of opioids may continue working and driving safety. The decision to allow patients to drive under stable long-term opioid therapy is always individually based and should be founded on relevant and up-to-date clinical data, including both physical and mental evaluations. The patient, on the other hand, should also be responsible for his condition before and during driving.

摘要

在过去十年中,为了提高患者的生活质量、允许其参与社交活动并重返工作岗位,许多欧洲国家使用阿片类药物长期治疗非恶性疼痛的情况急剧增加。因此,长期服用阿片类药物的患者驾车问题及其医学法律层面受到了医生、患者和社会的关注。许多研究使用健康受试者、因慢性恶性和非恶性疼痛服用阿片类药物的患者,采用不同给药方法并结合其他精神活性药物,探讨了阿片类药物对认知和驾驶技能的影响。这些研究表明,服用稳定剂量阿片类药物的患者可以继续安全地工作和驾驶。允许患者在长期稳定的阿片类药物治疗下驾驶的决定始终应基于个体情况,并应以相关的最新临床数据为依据,包括身体和心理评估。另一方面,患者在驾驶前和驾驶过程中也应对自己的状况负责。

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[Cerebral dysfunction after prolonged use of opioids].[长期使用阿片类药物后的脑功能障碍]
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