[Evaluation of primary cicatrization of anastomosis of small intestine (experimental study in guinea pigs)].

The healing process carried out during the first 72 hours of the anastomotic line of the small intestine has not been satisfactorily studied. This is a time during which intestinal transit is evaluated and oral feeding is given without being really sure whether there is resistance to rupture and if the open surgical technique favors local infection. For this study, 120 guinea pigs submitted to end-to-end anastomosis were used, 30 with continuous sutures and 30 with separate stitches, who were examined 24, 48 and 72 hours after the surgery, plus another group similarly evaluated immediately after the surgery, finding that rupture resistance is greater immediately after surgery than 48 or 72 hours later and that in these, the inflammatory process is greater and a more positive number of cultures are found. The antibiotic orally and parenterally administered did not do away with the infection but did limit further complications.