Boys Town National Research Hospital, Allergy, Asthma & Pediatric Pulmonology, Boys Town, NE 68010, USA.
Pulm Pharmacol Ther. 2010 Oct;23(5):384-8. doi: 10.1016/j.pupt.2010.06.001. Epub 2010 Jun 11.
Adherence to daily anti-inflammatory therapy, the cornerstone being inhaled corticosteroids (ICSs), is critical for the control of persistent asthma. Many factors, both behavioral and treatment-related, can affect treatment adherence. In the pediatric population, adherence is often the responsibility of parents/caregivers. Thus, parents may need improved awareness of the major asthma controller medications, especially regarding the efficacy and safety of ICSs; their beliefs or concerns regarding asthma therapy have a bearing on their diligence in encouraging adherence with the prescribed treatment regimen. Dosing complexity and factors relating to inhaler use are also important components of adherence. There are currently 6 ICSs (excluding nebulized ICSs) approved for children in the United States. The purpose of this review is to examine and compare the features of the available ICSs that may influence adherence in the treatment of pediatric asthma.
坚持每日抗炎治疗，其中基石是吸入皮质类固醇（ICSs），这对控制持续性哮喘至关重要。许多因素，包括行为和治疗相关的因素，都可能影响治疗的依从性。在儿科人群中，依从性通常是父母/照顾者的责任。因此，父母可能需要提高对主要哮喘控制药物的认识，特别是关于 ICSs 的疗效和安全性；他们对哮喘治疗的信念或担忧会影响他们督促患者遵守规定治疗方案的积极性。药物剂量复杂性和与吸入器使用相关的因素也是依从性的重要组成部分。目前，美国有 6 种 ICSs（不包括雾化 ICSs）被批准用于儿童。本文旨在检查和比较可用的 ICSs 的特性，这些特性可能会影响儿科哮喘治疗中的依从性。
