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脑性瘫痪儿童粗大运动和认知功能的全貌:性别差异。

Spectrum of gross motor and cognitive functions in children with cerebral palsy: gender differences.

机构信息

Division of Child Neurology and Psychiatry, Department of Paediatrics, University of Catania, Italy.

出版信息

Eur J Paediatr Neurol. 2011 Jan;15(1):53-8. doi: 10.1016/j.ejpn.2010.05.007. Epub 2010 Jun 9.

Abstract

BACKGROUND

Multiple differences between males and females are reported both in physiological and pathophysiological conditions.

AIMS

To test the hypothesis that gender could influence the motor and cognitive development in children with cerebral palsy (CP).

METHODS

Prospective, cross-sectional. One hundred seventy one children with CP (98 males and 73 females) were evaluated for motor (Gross Motor Function Measure, Gross Motor Function Classification System) and cognitive (Bayley II, Wechsler Scales) functions. Eighty-four of them were assessed before and other eighty-seven children after 4 years of age.

RESULTS

No gender-related differences were observed in children with diplegia or quadriplegia, both for motor and cognitive functions. On the contrary, females with hemiplegia scored significantly better (P < 0.01) in cognitive functions and in the dimension D (standing) of the Gross Motor Function Measure, under the age of 4 years. These differences were not observed after this age.

CONCLUSIONS

In this study we point out that gender might influence differently the psycho-motor development of children with hemiplegia and of those with a more severe clinical involvement as diplegia and quadriplegia.

摘要

背景

在生理和病理生理条件下,男性和女性之间存在多种差异。

目的

测试性别是否会影响脑瘫(CP)儿童的运动和认知发育的假设。

方法

前瞻性,横断面研究。171 名 CP 患儿(98 名男性和 73 名女性)进行了运动(粗大运动功能测量,粗大运动功能分类系统)和认知(贝利 II,韦氏量表)功能评估。其中 84 人在 4 岁之前进行了评估,另外 87 人在 4 岁之后进行了评估。

结果

在四肢瘫或双瘫的患儿中,无论在运动还是认知功能方面,均未观察到与性别相关的差异。相反,在 4 岁以下患有偏瘫的女性在认知功能和粗大运动功能测量的 D 维度(站立)方面得分显著更好(P <0.01)。这些差异在这个年龄之后没有被观察到。

结论

在这项研究中,我们指出性别可能会以不同的方式影响偏瘫和更严重的临床受累(如四肢瘫)的儿童的心理运动发育。

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