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纤维肌痛与肥胖症在疼痛、功能、情绪和睡眠方面的关系。

Relationship between fibromyalgia and obesity in pain, function, mood, and sleep.

机构信息

Pain Research and Management Center, Department of Anesthesiology, University of Utah, Salt Lake City, UT, USA.

出版信息

J Pain. 2010 Dec;11(12):1329-37. doi: 10.1016/j.jpain.2010.03.006. Epub 2010 Jun 9.

Abstract

UNLABELLED

Fibromyalgia syndrome (FMS) is a prevalent and disabling chronic pain disorder. Past research suggests that obesity is a common comorbidity and may be related to the severity of FMS. The main objective of the present study was to evaluate the relationships between FMS and obesity in the multiple FMS-related domains: hyperalgesia, symptoms, physical abilities, and sleep. A total of 215 FMS patients completed a set of self-report inventories to assess FMS-related symptoms and underwent the tender point (TP) examination, physical performance testing, and 7-day home sleep assessment. Forty-seven percent of our sample was obese and an additional 30% was overweight. Obesity was related significantly to greater pain sensitivity to TP palpation particularly in the lower body areas, reduced physical strength and lower-body flexibility, shorter sleep duration, and greater restlessness during sleep. The results confirmed that obesity is a prevalent comorbidity of FMS that may contribute to the severity of the problem. Potential mechanisms underlying the relationship are discussed.

PERSPECTIVE

This report presents how obesity may be interrelated to fibromyalgia pain, disability, and sleep. We found that obesity is common in FMS. Approximately half of our patients were obese and an additional 30% were overweight. We also found that obesity in FMS was associated with greater pain sensitivity, poorer sleep quality, and reduced physical strength and flexibility. The results suggest that obesity may aggregate FMS and weight management may need to be incorporated into treatments.

摘要

未标注

纤维肌痛综合征(FMS)是一种普遍存在且使人丧失能力的慢性疼痛障碍。过去的研究表明,肥胖是一种常见的合并症,并且可能与 FMS 的严重程度有关。本研究的主要目的是评估 FMS 在多个与 FMS 相关的领域中与肥胖之间的关系:痛觉过敏、症状、身体能力和睡眠。共有 215 名 FMS 患者完成了一套自我报告问卷,以评估与 FMS 相关的症状,并接受了压痛点(TP)检查、身体机能测试和 7 天家庭睡眠评估。我们样本的 47%是肥胖的,另外 30%是超重的。肥胖与对 TP 触诊的更高疼痛敏感性显著相关,尤其是在下半身区域,身体力量和下半身灵活性降低,睡眠时间缩短,睡眠时更不安宁。结果证实肥胖是 FMS 的一种普遍合并症,可能导致问题的严重程度增加。讨论了潜在的关系机制。

观点

本报告介绍了肥胖症如何与纤维肌痛的疼痛、残疾和睡眠相互关联。我们发现肥胖症在 FMS 中很常见。我们的患者中有大约一半是肥胖的,另外 30%是超重的。我们还发现,肥胖症与 FMS 相关的疼痛敏感性更高、睡眠质量更差以及身体力量和灵活性降低有关。结果表明,肥胖症可能会加剧 FMS,并且需要将体重管理纳入治疗中。

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