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大型听神经瘤经乙状窦后经外耳道入路手术后的长期面神经功能评估。

Long-term facial nerve function evaluation following surgery for large acoustic neuromas via retrosigmoid transmeatal approach.

机构信息

Department of Neurosurgery, the Second Hospital of Shandong University, Jinan, Shandong Province, China.

出版信息

Acta Neurochir (Wien). 2010 Oct;152(10):1647-52. doi: 10.1007/s00701-010-0705-7. Epub 2010 Jun 12.

Abstract

PURPOSE

By evaluating the postoperative facial nerve function of large acoustic neuromas, the purpose of this study was to analyze the factors that influence the facial nerve function outcome and to explore the surgical strategy for large acoustic neuromas.

METHODS

A retrospective study of surgical outcome was performed on 89 patients with large acoustic neuromas. All operations were performed via the retrosigmoid transmeatal approach using the intraoperative electrophysiological monitoring.

RESULTS

Gross total resection was performed in 38 (42.7%) of the 89 patients, near total resection in 35 (39.3%), and subtotal resection in 16 (18.0%). The facial nerve was anatomically intact at the end of surgery in 83 (93.3%) patients. At 1 year after surgery, 48 (53.9%) patients had good facial nerve function (House-Brackmann (HB) Grades I-II), 23 (25.8%) patients had regular facial nerve function (HB Grades III-IV), and 18 (20.2%) patients had poor facial nerve function (HB Grades V-VI).

CONCLUSIONS

For large acoustic neuromas, the goal of complete tumor resection and preservation of acceptable facial nerve function can be attained via the retrosigmoid transmeatal approach, using the intraoperative facial nerve monitoring. The surgical strategy of near total resection is indicated for the large acoustic neuromas with severe adherence or inclusion in order to preserve facial nerve function.

摘要

目的

通过评估大型听神经瘤患者的术后面神经功能,分析影响面神经功能预后的因素,并探讨大型听神经瘤的手术策略。

方法

对 89 例大型听神经瘤患者的手术结果进行回顾性研究。所有手术均采用经乙状窦后经外耳道入路,术中进行电生理监测。

结果

89 例患者中,38 例(42.7%)行全切除,35 例(39.3%)行近全切除,16 例(18.0%)行次全切除。83 例(93.3%)患者术后面神经解剖完整。术后 1 年,48 例(53.9%)患者面神经功能良好(House-Brackmann 分级 I-II),23 例(25.8%)患者面神经功能正常(HB 分级 III-IV),18 例(20.2%)患者面神经功能差(HB 分级 V-VI)。

结论

对于大型听神经瘤,通过经乙状窦后经外耳道入路,并采用术中面神经监测,可以达到完全切除肿瘤和保留可接受面神经功能的目标。对于严重粘连或包含的大型听神经瘤,行近全切除的手术策略有助于保留面神经功能。

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