Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, Ontario, Canada.
J Clin Exp Neuropsychol. 2010 Dec;32(10):1122-44. doi: 10.1080/13803391003781874. Epub 2010 Jun 9.
Studies of autobiographical recall in patients with major depressive disorder (MDD) reveal overgeneralization, where autobiographical memory (AM) comprises primarily factual or repeated information as opposed to details specific in time and in place and definitive of episodic re-experiencing. In addition to reviewing AM impairment in MDD, we explore the contribution of key method, demographic, and clinical variables to this dysfunction. Several candidate variables emerge, including testing method, emotion, mood state, illness burden, medication status, electroconvulsive therapy (ECT), comorbidity, trauma, age, ruminative state, and executive and memory function. These variables appear to interact in a complex manner to influence AM performance in MDD.
对患有重度抑郁症（MDD）的患者的自传体回忆进行的研究表明存在过度泛化现象，即自传体记忆（AM）主要由事实或重复信息组成，而不是具体时间和地点的详细信息，也不能明确体现情景重现。除了回顾 MDD 中的 AM 损伤外，我们还探讨了关键方法、人口统计学和临床变量对这种功能障碍的贡献。出现了一些候选变量，包括测试方法、情绪、心境状态、疾病负担、药物状态、电休克疗法（ECT）、合并症、创伤、年龄、沉思状态以及执行和记忆功能。这些变量似乎以复杂的方式相互作用，从而影响 MDD 中的 AM 表现。
