Adeyemi B F, Ogun G O, Akang E E
Department of Oral Pathology, College of Medicine, University of Ibadan, Nigeria.
West Afr J Med. 2010 Mar-Apr;29(2):98-103.
Salivary gland neoplasms constitute an important group of intraoral tumours, with their malignant histological types being the second most frequently diagnosed intraoral malignancy. The incidence as well as the anatomical distribution of this heterogeneous group of neoplasms varies from one racial group and geographical location to the other. However, studies from Africa on intraoral salivary gland neoplasms are relatively sparse in the medical literature.
To report the frequency and anatomical distribution of the various histological types of minor salivary gland neoplasms diagnosed at the University College Hospital, Ibadan and to provide data for comparison with other epidemiological findings in different geographic locations.
A retrospective study of intraoral salivary gland neoplasms diagnosed at the University Teaching Hospital, Ibadan between January I991- December 2007. Included in the study were charts of patients with minor salivary glands in the mouth. Information obtained about each patient included age, sex, tumour location and histological classification based on the 1991 WHO recommendations.
Of a total of 309 neoplasms of salivary gland origin, 92 were from the intra-oral minor salivary glands constituting 4.5% of head and neck neoplasm. There was no significant gender predilection. Fifty-seven (62%) cases were malignant, while 35 (38%) were benign. The most frequently diagnosed tumour was adenoid cystic carcinoma 35(38%), followed by pleomorphic adenoma 30(32.6%). About 73% of the salivary gland neoplasms affected the palate, followed by the buccal mucosa (16.3%). Patients with malignant neoplasms were about 10 years older than those with benign tumours (p=0.012).
A large proportion of intraoral salivary gland neoplasms are malignant, the most frequently affected site being the palate.
涎腺肿瘤是口腔内肿瘤的一个重要类别，其恶性组织学类型是口腔内第二常见的恶性肿瘤。这类异质性肿瘤的发病率以及解剖分布在不同种族群体和地理位置之间存在差异。然而，非洲关于口腔内涎腺肿瘤的研究在医学文献中相对较少。
报告在伊巴丹大学学院医院诊断出的各种组织学类型的小涎腺肿瘤的发生率及解剖分布，并提供数据以便与不同地理位置的其他流行病学研究结果进行比较。
对1991年1月至2007年12月在伊巴丹大学教学医院诊断出的口腔内涎腺肿瘤进行回顾性研究。纳入研究的是口腔内小涎腺患者的病历。获取的每位患者信息包括年龄、性别、肿瘤位置以及基于1991年世界卫生组织建议的组织学分类。
在总共309例涎腺源性肿瘤中，92例来自口腔内小涎腺，占头颈部肿瘤的4.5%。无明显性别倾向。57例（62%）为恶性，35例（38%）为良性。最常诊断出的肿瘤是腺样囊性癌35例（38%），其次是多形性腺瘤30例（32.6%）。约73%的涎腺肿瘤发生于腭部，其次是颊黏膜（16.3%）。恶性肿瘤患者比良性肿瘤患者大约年长10岁（p = 0.012）。
口腔内涎腺肿瘤中很大一部分是恶性的，最常受累部位是腭部。
