Kryzhanovskiĭ G N, Gorizontova M P, Igon'kina S I, Zinkevich V A, Speranskaia T V, Karganov M Iu
Biull Eksp Biol Med. 1991 Jan;111(1):9-11.
Biomicroscopic studies of mesentery in trigeminal neuralgia rats caused by creation of a generator of pathologically enhanced excitation in trigeminal nerve caudal nucleus (injection 0.25-1.0 DLM Tetanus toxin) have shown the microcirculatory disorders, venular permeability, mast cells degranulation, and an increase in lymphatic contractile activity. Microcirculatory disorders intensity and adaptation reaction appearance correlated with trigeminal neuralgia clinical picture.
对通过在三叉神经尾核中创建病理性增强兴奋发生器(注射0.25 - 1.0 DLM破伤风毒素)导致的三叉神经痛大鼠肠系膜进行生物显微镜研究,结果显示存在微循环障碍、小静脉通透性增加、肥大细胞脱颗粒以及淋巴收缩活动增强。微循环障碍的强度和适应性反应的出现与三叉神经痛的临床表现相关。