Brin B B, Tatrov A S
Biull Eksp Biol Med. 1991 Mar;111(3):244-5.
It has been shown that after parathyroid hormone (PTG) administration vasopressin increases the falling rate of the renal cortical blood flow and decreases the falling rate of the renal medullary blood flow in normotensive rats. In spontaneously hypertensive rats (SHR) the PTG decreases the falling rate of the cortical and medullary blood flow after vasopressin administration. PTG-induced hypercalcemia in SHR followed by vasopressin administration leads to the renal blood flow redistribution reaction due to which the medullary blood flow dominates over the cortical one.
研究表明,在给予甲状旁腺激素(PTG)后,血管加压素可使正常血压大鼠的肾皮质血流下降速率加快,使肾髓质血流下降速率减慢。在自发性高血压大鼠(SHR)中,给予PTG后可使血管加压素引起的皮质和髓质血流下降速率减慢。在SHR中,PTG诱导的高钙血症继以血管加压素给药会导致肾血流重新分布反应,由此髓质血流超过皮质血流。