运动预处理对恶性高热易感性肌肉热敏感性的影响。
Effect of prior exercise on thermal sensitivity of malignant hyperthermia-susceptible muscle.
机构信息
Department of Kinesiology & Health, PO Box 3975, Georgia State University, Atlanta, Georgia 30302-3975, USA.
出版信息
Muscle Nerve. 2010 Aug;42(2):270-2. doi: 10.1002/mus.21715.
Abstract
Malignant hyperthermia (MH) episodes may occur upon exposure to halogenated anesthetics, during resistance and endurance exercise, and in response to thermal stress. The purpose of this study was to investigate the effects of prior eccentric and concentric (i.e., wheel running) exercise on the thermal sensitivity of isolated MH-susceptible mouse muscle (RyR1(Y522S/wt)). Eccentric, but not concentric, exercise attenuated the thermal sensitivity of MH-susceptible muscle.
摘要
恶性高热（MH）发作可能发生在接触卤代麻醉剂、抵抗和耐力运动期间，以及对热应激的反应中。本研究的目的是探讨先前的离心和向心（即，车轮跑步）运动对分离的 MH 易感小鼠肌肉（RyR1(Y522S/wt)）的热敏感性的影响。离心运动，但不是向心运动，减轻了 MH 易感肌肉的热敏感性。
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