Timóteo Ana T, Branco Luísa M, Pinto Margarida, Bico Pedro, Ferreira Rui C
Serviço de Cardiologia, Hospital Santa Marta, Lisboa, Portugal.
Rev Port Cardiol. 2010 Feb;29(2):291-7.
Nocardia causes several types of infection in both immunocompetent and immunocompromised hosts, and may affect any organ. Endocarditis due to infection by Nocardia species is rare and has a poor prognosis. To our knowledge, after a literature review, only 12 cases of nocardial endocarditis have been reported, most treated with valve replacement. We report the case of a patient with prosthetic valve endocarditis due to Nocardia species, who was successfully treated with antimicrobial chemotherapy only (trimethoprim-sulfamethoxazole), instead of valve replacement.
诺卡菌可在免疫功能正常和免疫功能低下的宿主中引起多种类型的感染，并可能累及任何器官。诺卡菌属感染所致的心内膜炎较为罕见，预后较差。据我们所知，经文献回顾后，仅报告了12例诺卡菌性心内膜炎病例，大多数病例采用瓣膜置换术治疗。我们报告了1例因诺卡菌属导致人工瓣膜心内膜炎的患者，该患者仅通过抗菌化疗（甲氧苄啶-磺胺甲恶唑）成功治愈，而未进行瓣膜置换。
