Department of Extracorporeal Circulation, St. Antonius Hospital, Nieuwegein, The Netherlands.
Artif Organs. 2010 Dec;34(12):1092-8. doi: 10.1111/j.1525-1594.2009.00986.x.
The use of minimized extracorporeal circuits (MECC) in cardiac surgery is expanding. These circuits eliminate volume storage and bubble trap reservoirs to minimize the circuit. However, this may increase the risk of gaseous micro emboli (GME). To reduce this risk, a venous bubble trap was designed. This study was performed to evaluate if incorporation of a venous bubble trap in a MECC system as compared to our standard minimized extracorporeal circuit without venous bubble trap reduces gaseous micro emboli during cardiopulmonary bypass (CPB). Forty patients were randomly assigned to be perfused either with or without an integrated venous bubble trap. After preliminary evaluation of the data of 23 patients, the study was terminated prior to study completion. The quantity and volume of GME were significantly lower in patients perfused with a venous bubble trap compared to patients perfused without a venous bubble trap. The present study demonstrates that a MECC system with a venous bubble trap significantly reduces the volume of GME and strongly reduces the quantity of large GME (>500 µm). Therefore, the use of a venous bubble trap in a MECC system is warranted.
心脏手术中使用最小化体外循环（MECC）的情况正在增加。这些回路消除了体积储存和气泡陷阱储液器，以最小化回路。然而，这可能会增加气体微栓塞（GME）的风险。为了降低这种风险，设计了一种静脉气泡捕集器。本研究旨在评估与没有静脉气泡捕集器的标准最小化体外循环系统相比，在体外循环（CPB）期间，将静脉气泡捕集器纳入 MECC 系统是否会减少气体微栓塞。将 40 名患者随机分为接受或不接受集成静脉气泡捕集器的灌注。在对 23 名患者的数据进行初步评估后，在完成研究之前提前终止了研究。与未使用静脉气泡捕集器的患者相比，使用静脉气泡捕集器的患者的 GME 数量和体积明显降低。本研究表明，带有静脉气泡捕集器的 MECC 系统可显著减少 GME 的体积，并强烈减少大 GME（> 500 µm）的数量。因此，MECC 系统中使用静脉气泡捕集器是合理的。
