Chaichudchaval Poonnapa, Fuangkamonvet Nunthapat, Piboonlapudom Supajitra, Chanthasopeephan Teeranoot
Department of Mechanical Engineering, Faculty of Engineering, King Mongkut's University of Technology Thonburi, Bangkok, 10150, Thailand.
BMC Biomed Eng. 2023 Apr 1;5(1):2. doi: 10.1186/s42490-023-00069-3.
This paper sets out to design a device for removing bubbles during the process of hemodialysis. The concept is to guide the bubbles while traveling through the device and eventually the bubbles can be collected. The design focuses on the analysis of various parameters i.e. inlet diameter, inlet velocity and size of the pitch. The initial diameters of Models 1 and 2 have thread regions of 6 and 10 mm, respectively.
Swirl number, Taylor number, Lift coefficient along with pressure field are also implemented.
Based on computational fluid dynamics analysis, the bubbles' average maximum equilibrium position for Model 1 reached 1.995 mm, being greater than that of Model 2, which attained 1.833 mm. Then, 16,000 bubbles were released into Model 1 to validate the performance of the model. This number of bubbles is typically found in the dialysis. Thus, it was found that 81.53% of bubbles passed through the radial region of 2.20 ± 0.30 mm. The appropriate collecting plane was at 100 mm, as measured from the inlet position along the axial axis. The Taylor number, Lift coefficient, and Swirl number proved to be significant parameters for describing the movement of the bubbles. Results were based on multiple inlet velocities. It is seen that Model 3, the improved model with unequal pitch, reached a maximum equilibrium position of 2.24 mm.
Overall, results demonstrated that Model 1 was the best design compared to Models 2 and 3. Model 1 was found capable of guiding the bubbles to the edge location and did not generate extra bubbles. Thus, the parametric study, herein, can be used as a prototype for removing bubbles during the process of hemodialysis.
本文旨在设计一种用于血液透析过程中去除气泡的装置。其理念是在气泡通过该装置时对其进行引导,最终实现气泡的收集。该设计着重于对各种参数的分析,即入口直径、入口速度和螺距尺寸。模型1和模型2的初始直径分别具有6毫米和10毫米的螺纹区域。
还计算了涡旋数、泰勒数、升力系数以及压力场。
基于计算流体动力学分析,模型1中气泡的平均最大平衡位置达到1.995毫米,大于模型2的1.833毫米。然后,向模型1中释放16000个气泡以验证该模型的性能。这个气泡数量在透析中较为常见。结果发现,81.53%的气泡通过了2.20±0.30毫米的径向区域。合适的收集平面位于沿轴向从入口位置测量的100毫米处。事实证明,泰勒数、升力系数和涡旋数是描述气泡运动的重要参数。结果基于多个入口速度。可以看到,改进后的不等螺距模型3的最大平衡位置达到了2.24毫米。
总体而言,结果表明与模型2和模型3相比,模型1是最佳设计。发现模型1能够将气泡引导至边缘位置且不会产生额外气泡。因此,本文中的参数研究可作为血液透析过程中去除气泡的原型。