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乳腺血液系统恶性肿瘤的 FDG PET/CT 表现。

FDG PET/CT manifestations of hematopoietic malignancies of the breast.

机构信息

Department of Imaging Science, University of Rochester Medical Center, NY 14642, USA.

出版信息

Acad Radiol. 2010 Aug;17(8):1026-30. doi: 10.1016/j.acra.2010.03.023. Epub 2010 Jun 14.

DOI:10.1016/j.acra.2010.03.023
PMID:20547460
Abstract

Hematopoietic malignancies that can be encountered in the breast include lymphoma, leukemia, and multiple myeloma/plasmacytoma. These are readily imaged via [18]F-fluorodeoxyglucose position emission tomography (PET)/computed tomography (CT) and can manifest as unilateral, bilateral, single, multiple, round/oval masses, or diffuse. These malignancies can occasionally mimic primary breast cancers. Conversely, benign conditions, such as the lactating breast can resemble hematopoietic malignancies of the breast. Although uncommon, familiarity with hematopoietic malignancies of the breast is important for proper interpretation of PET/CT. In this pictorial review, the PET/CT imaging features of patients with hematopoietic malignancies of the breast will be described, including pathology-proven cases of acute myelogenous leukemia, diffuse B-cell lymphoma, follicular lymphoma, acute myeloid leukemia with neutropenic granulocytic) sarcoma, and plasmacytoma. In addition, potential pitfalls will be discussed.

摘要

在乳房中可遇到的造血系统恶性肿瘤包括淋巴瘤、白血病和多发性骨髓瘤/浆细胞瘤。这些疾病可以通过 [18]F-氟脱氧葡萄糖位置发射断层扫描(PET)/计算机断层扫描(CT)进行成像,并且可以表现为单侧、双侧、单发、多发、圆形/椭圆形肿块或弥漫性。这些恶性肿瘤偶尔可能类似于原发性乳腺癌。相反,良性疾病,如哺乳期乳房,也可能类似于乳房的造血系统恶性肿瘤。虽然不常见,但熟悉乳房造血系统恶性肿瘤对于正确解读 PET/CT 非常重要。在这篇图像综述中,将描述乳房造血系统恶性肿瘤患者的 PET/CT 成像特征,包括经病理证实的急性髓系白血病、弥漫性 B 细胞淋巴瘤、滤泡性淋巴瘤、伴有中性粒细胞肉瘤的急性髓系白血病和浆细胞瘤。此外,还将讨论潜在的陷阱。

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