1例重症肌无力患者合并孤立性丛状神经纤维瘤。
A case of isolated plexiform neurofibroma in a patient with myasthenia gravis.
作者信息
Back Seung Ju, Kim Dae Hun, Kim Nari, Lee Young, Seo Young Joon, Park Jang Kyu, Lee Jeung Hoon
机构信息
Department of Dermatology, College of Medicine, Chungnam National University, Daejeon, Korea.
出版信息
Ann Dermatol. 2009 Feb;21(1):53-5. doi: 10.5021/ad.2009.21.1.53. Epub 2009 Feb 28.
We report a case of an isolated plexiform neurofibroma occurring in a patient with myasthenia gravis. A 48-year-old man presented with asymptomatic skin-colored nodules on the tip of his 4th finger. Microscopically, a plexiform neurofibroma was identified located in the dermis that appeared to originate from small superficial nerves. He had a 20-year history of treated myasthenia gravis; otherwise, his personal and family histories were unremarkable. Given that myasthenia gravis is a disorder of the peripheral nerves, plexiform neurofibromas could be associated with myasthenia gravis. However, the development of an isolated plexiform neurofibroma in a case of myasthenia gravis has not yet been reported. The occurrence of a neurofibromas in a patient with myasthenia gravis suggests a link in the pathogenesis of these two diseases.
我们报告一例重症肌无力患者发生孤立性丛状神经纤维瘤的病例。一名48岁男性，其右手无名指指尖出现无症状的肤色结节。显微镜检查发现，位于真皮层的丛状神经纤维瘤似乎起源于浅表小神经。他有20年重症肌无力治疗史；除此之外，其个人史和家族史均无异常。鉴于重症肌无力是一种周围神经疾病，丛状神经纤维瘤可能与重症肌无力有关。然而，重症肌无力患者发生孤立性丛状神经纤维瘤的情况尚未见报道。重症肌无力患者出现神经纤维瘤提示这两种疾病在发病机制上存在联系。
Zotero 插件