一项前瞻性研究，证明了在巴拉圭，5%聚维酮碘应用于眼前段眼内手术的效果。

A prospective study demonstrating the effect of 5% povidone-iodine application for anterior segment intraocular surgery in Paraguay.

作者信息

Quiroga Lorena P, Lansingh Van, Laspina Florentina, Samudio Margarita, Stanley Jenny, Kaspar Herminia Miño de, Cibils Diógenes, Cibils Pablo

机构信息

Instituto de Previsión Social, Fundacion Vision e Central Hospital, Asunción, Paraguay.

出版信息

Arq Bras Oftalmol. 2010 Mar-Apr;73(2):125-8. doi: 10.1590/s0004-27492010000200005.

DOI:10.1590/s0004-27492010000200005

PMID:20549039

Abstract

PURPOSE

To determine the conjunctival bacterial flora in cataract surgery patients and the effect of presurgical irrigation with 5% povidone-iodine solution.

METHODS

Three samples from the inferior conjunctival fornix of the eye to be operated were obtained at baseline before washing (T0) with 10 ml 5% povidone-iodine solution, immediately after washing (T1), and upon completion of surgery (T2). Bacteria from the samples were inoculated in blood agar, chocolate agar, and thioglycolate broth.

RESULTS

A total of 221 patients (n=224 eyes) with a mean age of 67 +/- 13 years were included in the study. Bacteria from the (T0) samples were successfully grown in 73.2% of the thioglycolate agars, 21.0% of the blood agars, and 19.2% of the chocolate agars. Compared with T1 samples, the use of povidone-iodine wash translated into a 60.8% reduction (from 73.2% to 12.5%) in colonization of the conjunctiva (p<0.001), while no significant difference was found between the T1 and T2 samples.

CONCLUSION

Conjunctival irrigation with a 5% povidone-iodine solution effectively reduces conjunctival flora and is therefore strongly recommended as a means of preventing postsurgical endophthalmitis following cataract surgery.

摘要

目的

确定白内障手术患者的结膜细菌菌群以及术前用5%聚维酮碘溶液冲洗的效果。

方法

在使用10 ml 5%聚维酮碘溶液冲洗前（T0）、冲洗后立即（T1）以及手术完成时（T2），从拟手术眼的下结膜穹窿处获取三个样本。将样本中的细菌接种于血琼脂、巧克力琼脂和硫乙醇酸盐肉汤中。

结果

共有221例患者（n = 224只眼）纳入研究，平均年龄为67±13岁。来自（T0）样本的细菌在73.2%的硫乙醇酸盐琼脂、21.0%的血琼脂和19.2%的巧克力琼脂中成功生长。与T1样本相比，使用聚维酮碘冲洗使结膜定植减少了60.8%（从73.2%降至12.5%）（p<0.001），而T1和T2样本之间未发现显著差异。