Blume A
Fachbereich Chemie, Universität Kaiserslautern, F.R.G.
Chem Phys Lipids. 1991 Mar;57(2-3):253-73. doi: 10.1016/0009-3084(91)90080-u.
Polymerizable lipids have received considerable attention in the last ten years as polymerization of lipids in vesicle systems is a possibility to increase the stability of lipid bilayers. Lipids with various polymerizable groups have been synthesized in the last years. This paper is focussed on those lipids which are closely related to natural phospholipids, i.e. molecules which have two hydrophobic chains and a head group containing a phosphate moiety. The phase behaviour of polymerizable phospholipids as lipid monomers and in the polymerized state is reviewed and discussed.
在过去十年中，可聚合脂质受到了广泛关注，因为在囊泡系统中脂质的聚合是提高脂质双层稳定性的一种可能途径。近年来，人们合成了具有各种可聚合基团的脂质。本文重点关注那些与天然磷脂密切相关的脂质，即具有两条疏水链和一个含磷酸部分的头部基团的分子。本文综述并讨论了可聚合磷脂作为脂质单体以及聚合状态下的相行为。
