[Nutritional and metabolic evaluation of patients after one year of gastric bypass surgery].

OBJECTIVE

To assess nutritional and metabolic evolution and inflammatory activity in severe obese patients submitted to bariatric surgery.

METHODS

This prospective study evaluated 56 patients (50 female and 6 male), mean age 40 + or - 9,9 years, submitted to RYGB. Nutritional, metabolic, and inflammatory parameters were assessed prior to and 12 months postsurgery.

RESULTS

It was verified significant decreases in weight loss in relation to baseline values from 138 + or - 28,8 to 90 + or - 19,5 kg (p< 0,0001), glucose levels from 116 + or - 47,3 to 84 + or - 9,8 mg/dL (p< 0,0001), triacylglycerol levels from 137 + or - 61,4 to 84 + or - 38,6 mg/dL (p< 0,0001), and also in total cholesterol from 189 + or - 41,6 to 166 + or - 36,4 mg/dL (p< 0,0001) and LDL-cholesterol from 119 + or - 36,1 to 104 + or - 30,7 mg/dL (p< 0,0005). C-reactive protein levels reduced from 11,33 + or - 10,82 to 3,62 + or - 4,49 mg/dL (p< 0,0001). Although maintenance of iron levels was verified after one year, there was a significant decrease in hemoglobin from 13 + or - 1,3 to 12 + or - 1,4 g/dL (p< 0,01), and reduction in ferritin levels, especially in women who showed a decrease from 101,2 + or - 123,3 to 85,0 + or - 101,9 (p< 0,03).

CONCLUSION

Therefore, weigh loss in patients with severe obese after RYGB showed improvement in both metabolic and inflammatory status and may reduce substantially co-morbidities associated with increased cardiovascular risk.