Aguilar A J, Fonseca L, Croxatto J O
Department of Ophthalmology, Hospital Rivadavia, Buenos Aires, Argentina.
Cornea. 1991 May;10(3):203-6. doi: 10.1097/00003226-199105000-00003.
The diagnosis of Sjogren's syndrome (SJ) as an underlying disease of keratoconjunctivitis sicca is important because of the many ocular and systemic complications. We compared the results of impression cytology of conjunctiva (ICC) and the results of labial salivary gland biopsy (LSB) with impression cytology of buccal mucosa (ICB) in 33 patients with SJ. LSB, ICC, and ICB were considered positive in all patients. Moderate to severe changes were graded in 85% of the biopsy specimens, 94% of the conjunctival specimens, and 76% of the buccal mucosa specimens. The rate of agreement between LSB and ICB was 97%. The use of ICB in the clinical ophthalmological examination may be helpful in patients with consistent history, and clinical and ocular findings, before the biopsy procedure.
由于存在许多眼部和全身并发症，将干燥综合征（SJ）诊断为干燥性角结膜炎的潜在病因很重要。我们比较了33例SJ患者的结膜印片细胞学检查（ICC）结果、唇唾液腺活检（LSB）结果与颊黏膜印片细胞学检查（ICB）结果。所有患者的LSB、ICC和ICB均被视为阳性。85%的活检标本、94%的结膜标本和76%的颊黏膜标本出现中度至重度变化。LSB和ICB之间的一致率为97%。在活检程序之前，对于有一致病史、临床和眼部表现的患者，在临床眼科检查中使用ICB可能会有帮助。
