Department of Bioengineering, University of California-San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Bioinformatics. 2010 Aug 1;26(15):1915-7. doi: 10.1093/bioinformatics/btq296. Epub 2010 Jun 15.
ViewDock TDW is a modification of the pre-existing ViewDock Chimera extension (http://www.cgl.ucsf.edu/chimera/) used to visualize results of virtual screening experiments. By combing TDW hardware and an enhanced ViewDock interface, dozens of ligand-protein complexes are rendered simultaneously to parallelize the analysis of candidate ligands. The ViewDock TDW GUI allows the user to easily and interactively manipulate the molecules on the TDW as an entire set, a selected subset or a single ligand-protein complex and preserves all Chimera functionality.
ViewDock TDW is an open source software; freely available on the web at http://www.tdw-prime.webs.com. Chimera UCSF is also available, free of charge, at http://www.cgl.ucsf.edu/chimera/
ViewDock TDW 是对现有 ViewDock Chimera 扩展(http://www.cgl.ucsf.edu/chimera/)的修改,用于可视化虚拟筛选实验的结果。通过结合 TDW 硬件和增强的 ViewDock 界面,可以同时渲染数十个配体-蛋白质复合物,从而实现候选配体分析的并行化。ViewDock TDW 的图形用户界面允许用户轻松地交互操作 TDW 上的分子作为一个整体、一个选定的子集或一个单独的配体-蛋白质复合物,并保留所有 Chimera 的功能。
ViewDock TDW 是一个开源软件;可在网页上免费获取,网址是 http://www.tdw-prime.webs.com。Chimera UCSF 也可在免费获取,网址是 http://www.cgl.ucsf.edu/chimera/