Center for Bioinformatics, Bilkent University, Ankara, Turkey.
Bioinformatics. 2010 Feb 1;26(3):429-31. doi: 10.1093/bioinformatics/btp665. Epub 2009 Dec 9.
Representing models of cellular processes or pathways in a graphically rich form facilitates interpretation of biological observations and generation of new hypotheses. Solving biological problems using large pathway datasets requires software that can combine data mapping, querying and visualization as well as providing access to diverse data resources on the Internet. ChiBE is an open source software application that features user-friendly multi-view display, navigation and manipulation of pathway models in BioPAX format. Pathway views are rendered in a feature-rich format, and may be laid out and edited with state-of-the-art visualization methods, including compound or nested structures for visualizing cellular compartments and molecular complexes. Users can easily query and visualize pathways through an integrated Pathway Commons query tool and analyze molecular profiles in pathway context.
http://www.bilkent.edu.tr/%7Ebcbi/chibe.html.
Supplementary data are available at Bioinformatics online.
以图形化的方式展示细胞过程或通路模型，有助于解释生物学观察结果并生成新的假说。使用大型通路数据集解决生物学问题需要能够将数据映射、查询和可视化相结合的软件，并且能够访问互联网上的各种数据资源。ChiBE 是一个开源软件应用程序，具有用户友好的多视图显示、BioPAX 格式的通路模型的导航和操作功能。通路视图以功能丰富的格式呈现，可以使用最先进的可视化方法进行布局和编辑，包括用于可视化细胞区室和分子复合物的复合或嵌套结构。用户可以通过集成的通路 Commons 查询工具轻松查询和可视化通路，并在通路上下文中分析分子谱。
http://www.bilkent.edu.tr/%7Ebcbi/chibe.html。
补充数据可在 Bioinformatics 在线获得。
