Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388-1 Pungnap 2-dong, Songpa-ku, Seoul 138-736, Korea.
Radiology. 2010 Aug;256(2):433-40. doi: 10.1148/radiol.10091897. Epub 2010 Jun 15.
To determine the relative accuracy of automated blood-free to blood-filled computed tomographic (CT) volumetry for estimation of right-lobe weight in living donor liver transplantation.
This retrospective study was approved by the institutional review board; informed consent was waived. Between October 1, 2008, and April 30, 2009, 88 live liver donors (54 men, 34 women; mean age, 26.1 years +/- 6.9 [standard deviation]) who underwent CT and had their right lobes procured in the study institution were included. Automated measurement of blood-filled volume (V(BFill)) and blood-free volume (V(BFree)) of the right lobe was performed by using 16-row multidetector CT performed with 5-mm intervals. Actual hepatic weight was measured blood free during surgery. Percentage blood volume, %V(B), was calculated as follows: %V(B) = V(BFill) - V(BFree)/V(BFill) . 100. Pearson tests were performed to determine correlation coefficients between V(BFill)/1.22 or V(BFree) and weight. Percentage deviation and percentage absolute deviation of V(BFree) from weight were compared with those of V(BFill)/1.22 by using a paired t test or Wilcoxon rank sum test. Regression analysis was performed between V(BFree) and weight.
Mean V(BFill), V(BFree), and weight were 789.0 mL +/- 126.4, 713.9 mL +/- 114.4, and 717.8 g +/- 110.4. Percentage blood volume varied from 6.5% to 19.8% (mean, 9.5%). Compared with weight, the correlation coefficient was slightly higher with V(BFree) (r = 0.9140) than with V(BFill)/1.22 (r = 0.8909). Mean percentage deviation and percentage absolute deviation were significantly smaller with V(BFree) (-0.4% +/- 6.3, 5.0% +/- 3.8; P < .001) than with V(BFill)/1.22 (-9.8% +/- 6.5, 10.2% +/- 7.3; P < .001). The equation relating V(BFree) and weight, W, was as follows: W = (0.8815 . V(BFree)) + 88.5117, with R(2) of 0.8355 (P < .001).
At automated CT volumetry in live liver donors, the percentage blood volume varies. The V(BFree) is more accurate than is V(BFill)/1.22 in estimation of hepatic weight.
确定自动化无血到血填充计算机断层扫描（CT）体积测量用于活体肝移植中右叶重量估计的相对准确性。
本回顾性研究获得机构审查委员会批准；豁免知情同意。2008 年 10 月 1 日至 2009 年 4 月 30 日期间，在研究机构进行 CT 检查并获取右叶的 88 名活体供肝者（54 名男性，34 名女性；平均年龄 26.1 岁 +/- 6.9[标准差]）被纳入本研究。使用 16 层多排 CT 以 5mm 间隔进行右叶血填充体积（V（BFill））和无血填充体积（V（BFree））的自动测量。实际肝重量在手术期间无血测量。通过以下公式计算血容量百分比，%V（B）：%V（B）= V（BFill）- V（BFree）/V（BFill）. 100。使用 Pearson 检验确定 V（BFill）/1.22 或 V（BFree）与重量之间的相关系数。使用配对 t 检验或 Wilcoxon 秩和检验比较 V（BFree）与重量之间的百分比偏差和百分比绝对偏差。对 V（BFree）与重量之间进行回归分析。
平均 V（BFill）、V（BFree）和重量分别为 789.0ml +/- 126.4、713.9ml +/- 114.4 和 717.8g +/- 110.4。血容量百分比为 6.5%至 19.8%（平均值为 9.5%）。与重量相比，V（BFree）的相关系数（r = 0.9140）略高于 V（BFill）/1.22（r = 0.8909）。V（BFree）的平均百分比偏差和百分比绝对偏差明显小于 V（BFill）/1.22（-0.4% +/- 6.3，5.0% +/- 3.8；P <.001）。V（BFree）与重量（W）的关系式为：W =（0.8815. V（BFree））+ 88.5117，R2 为 0.8355（P <.001）。
在活体肝供者的自动化 CT 体积测量中，血容量百分比会发生变化。与 V（BFill）/1.22 相比，V（BFree）在估计肝重量方面更准确。
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