Alcohol and Drug Abuse Institute, University of Washington, Seattle, WA 98105, USA.
Clin J Pain. 2010 Jul-Aug;26(6):489-97. doi: 10.1097/AJP.0b013e3181e103d9.
Chronic opioid therapy for chronic noncancer pain has increased dramatically in recent years. Research on associated risks has typically focused on opioid abuse and dependence, and opioid misuse or aberrant drug use behaviors, but these risks have been defined from the providers' perspective. The aim of this article was to develop a psychometrically sound method for assessing difficulties patients attribute to chronic opioid therapy.
A cross-sectional, observational study of patients prescribed opioids for chronic noncancer pain was conducted in a large integrated service delivery network in Washington State. Data were obtained from a phone interview and electronic health records including pharmacy data. Exploratory and confirmatory factor analyses were conducted using a split sample design.
The interview response rate was 56.5% and a total of 1144 patients were included in analyses. A 2 factor solution was obtained and replicated with excellent fit statistics. Two correlated factors were identified-opioid control concerns and psychosocial problems-with 50% of the sample reporting difficulties with prescribed opioids: 24% reported elevated psychosocial problems and 36% reported elevated concerns about controlling their use of prescribed opioids.
The Prescribed Opioid Difficulties Scale identifies common difficulties that patients ascribe to chronic opioid therapy. This scale may provide both an entry point and a framework for a patient-centered clinical dialog about the pros and cons of use of opioid medicines for managing chronic pain.
近年来,慢性非癌性疼痛的慢性阿片类药物治疗显著增加。与相关风险相关的研究通常侧重于阿片类药物滥用和依赖,以及阿片类药物滥用或异常药物使用行为,但这些风险是从提供者的角度来定义的。本文的目的是开发一种具有良好心理测量学特性的方法,用于评估患者归因于慢性阿片类药物治疗的困难。
在华盛顿州的一个大型综合服务提供网络中,对接受阿片类药物治疗慢性非癌性疼痛的患者进行了一项横断面、观察性研究。数据来自电话访谈和电子健康记录,包括药房数据。使用拆分样本设计进行探索性和验证性因子分析。
访谈的回复率为 56.5%,共有 1144 名患者纳入分析。获得了一个 2 因素解决方案,并通过良好的拟合统计数据进行了复制。确定了两个相关的因素——阿片类药物控制问题和心理社会问题——50%的样本报告了与处方阿片类药物相关的困难:24%报告了升高的心理社会问题,36%报告了对控制处方阿片类药物使用的担忧增加。
处方阿片类药物困难量表识别了患者归因于慢性阿片类药物治疗的常见困难。该量表可以为以患者为中心的关于使用阿片类药物治疗慢性疼痛的利弊的临床对话提供一个切入点和框架。