FKBP5 polymorphisms modify the effects of childhood trauma.
作者信息
Koenen Karestan C, Uddin Monica
机构信息
Department of Society, Human Development, and Health and Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.
出版信息
Neuropsychopharmacology. 2010 Jul;35(8):1623-4. doi: 10.1038/npp.2010.60.
Abstract
摘要
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FKBP5 polymorphisms modify the effects of childhood trauma.
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本文引用的文献
1
Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder.FKBP5 与儿童期逆境相互作用对创伤后应激障碍的风险。
Neuropsychopharmacology. 2010 Jul;35(8):1684-92. doi: 10.1038/npp.2010.37. Epub 2010 Apr 14.
2
Race/ethnic differences in exposure to traumatic events, development of post-traumatic stress disorder, and treatment-seeking for post-traumatic stress disorder in the United States.在美国，种族/民族差异与创伤事件的暴露、创伤后应激障碍的发展以及创伤后应激障碍的治疗寻求有关。
Psychol Med. 2011 Jan;41(1):71-83. doi: 10.1017/S0033291710000401. Epub 2010 Mar 29.
3
Interaction of FKBP5, a stress-related gene, with childhood trauma increases the risk for attempting suicide.应激相关基因 FKBP5 与儿童期创伤相互作用会增加自杀未遂的风险。
Neuropsychopharmacology. 2010 Jul;35(8):1674-83. doi: 10.1038/npp.2009.236. Epub 2010 Jan 20.
4
Protective effect of CRHR1 gene variants on the development of adult depression following childhood maltreatment: replication and extension.促肾上腺皮质激素释放激素受体1（CRHR1）基因变异对童年期受虐后成人抑郁症发生的保护作用：重复验证与拓展
Arch Gen Psychiatry. 2009 Sep;66(9):978-85. doi: 10.1001/archgenpsychiatry.2009.114.
5
Effects of stress throughout the lifespan on the brain, behaviour and cognition.一生中压力对大脑、行为和认知的影响。
Nat Rev Neurosci. 2009 Jun;10(6):434-45. doi: 10.1038/nrn2639. Epub 2009 Apr 29.
6
Neurobiology of posttraumatic stress disorder.创伤后应激障碍的神经生物学
CNS Spectr. 2009 Jan;14(1 Suppl 1):13-24.
7
Alcohol self-administration acutely stimulates the hypothalamic-pituitary-adrenal axis, but alcohol dependence leads to a dampened neuroendocrine state.急性酒精自我给药会刺激下丘脑-垂体-肾上腺轴，但酒精依赖会导致神经内分泌状态受到抑制。
Eur J Neurosci. 2008 Oct;28(8):1641-53. doi: 10.1111/j.1460-9568.2008.06455.x.
8
Polymorphisms in the FKBP5 gene region modulate recovery from psychosocial stress in healthy controls.FKBP5基因区域的多态性调节健康对照组从心理社会压力中的恢复情况。
Eur J Neurosci. 2008 Jul;28(2):389-98. doi: 10.1111/j.1460-9568.2008.06332.x.
9
Association of FKBP5 polymorphisms and childhood abuse with risk of posttraumatic stress disorder symptoms in adults.FKBP5基因多态性与童年期虐待经历和成年人创伤后应激障碍症状风险的关联。
JAMA. 2008 Mar 19;299(11):1291-305. doi: 10.1001/jama.299.11.1291.
10
The enduring effects of abuse and related adverse experiences in childhood. A convergence of evidence from neurobiology and epidemiology.童年期虐待及相关不良经历的持久影响。神经生物学与流行病学证据的汇聚。
Eur Arch Psychiatry Clin Neurosci. 2006 Apr;256(3):174-86. doi: 10.1007/s00406-005-0624-4. Epub 2005 Nov 29.
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