[原发性干燥综合征与视神经脊髓炎]

[Primary Sjögren's syndrome and neuromyelitis optica].

作者信息

Chourkani N, El Moutawakil B, Sibai M, Bourezgui M, Rafai M A, Slassi I

机构信息

Service de neurologie et d'explorations fonctionnelles, CHU Ibn Rochd, quartier des hôpitaux, Casablanca, Maroc.

出版信息

Rev Med Interne. 2010 Sep;31(9):e13-5. doi: 10.1016/j.revmed.2009.08.018.

DOI:10.1016/j.revmed.2009.08.018

PMID:20554086

Abstract

Neuromyelitis optica (NMO) is characterized by the association of optic neuritis and myelitis without any other neurological signs. In 30 % of the cases, NMO is associated with a systemic disorders. We report two cases of NMO associated with primary Sjögren's syndrome that was diagnosed during an acute flare of NMO. The relationship between NMO and Sjögren's syndrome has not been clearly identified. This association likely reflects the coexistence of two autoimmune disorders. The prognosis of NMO appears to be more severe in patients having coexisting Sjögren's syndrome, which renders useful to search for this association in patients with neuromyelitis optica.

摘要

视神经脊髓炎（NMO）的特征是视神经炎和脊髓炎同时存在，而无任何其他神经体征。在30%的病例中，NMO与全身性疾病相关。我们报告了两例在NMO急性发作期间被诊断为与原发性干燥综合征相关的NMO病例。NMO与干燥综合征之间的关系尚未明确。这种关联可能反映了两种自身免疫性疾病的共存。对于患有干燥综合征的视神经脊髓炎患者，NMO的预后似乎更严重，这使得在视神经脊髓炎患者中寻找这种关联很有必要。