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利妥昔单抗治疗干燥综合征合并视神经脊髓炎的疗效:病例报告及文献复习

The efficacy of rituximab in the therapy of neuromyelitis optica in a patient with Sjogren's syndrome: case-report and literature review.

作者信息

Torgashina A V, Vasilyev V I

机构信息

V.A. Nasonova Research Institute of Rheumatology, Moscow, Russia.

出版信息

Ter Arkh. 2018 May 11;90(5):76-80. doi: 10.26442/terarkh201890576-80.

Abstract

This case is the first description of the successful anti-B-cell therapy with rituximab in a patient with Sjogren's syndrome and neuromyelitis optica spectrum disorder in Russia. This article contains the literature data on clinical manifestations and methods of the diagnosis of neuromyelitis optica spectrum disorder. Furthermore, contemporary view on the pathogenesis of the combination of this disease with Sjogren's syndrome are presented here.

摘要

该病例是俄罗斯首例关于利妥昔单抗成功治疗干燥综合征合并视神经脊髓炎谱系障碍患者的报道。本文包含了视神经脊髓炎谱系障碍临床表现及诊断方法的文献资料。此外,还阐述了目前对于该疾病与干燥综合征合并发病机制的观点。

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