Skull Base Surgery Center, Capital Medical University Xuanwu Hospital, No. 45 Changchun Street, XuanWu District, Beijing 100053, China.
J Clin Neurosci. 2010 Aug;17(8):1083-5. doi: 10.1016/j.jocn.2009.12.012.
We report a patient with a tiny intradural clival chordoma, which was identified following presentation with cerebrospinal fluid (CSF) rhinorrhea as the initial symptom. The transclival dural defect and the intradural tumor were successfully localized by both radiological investigation and intraoperative endoscopic inspection. The tumor was totally resected and the CSF fistula was repaired by an endoscopic endonasal approach. The diagnosis, possible mechanisms and management of this rare condition are discussed. The role of endoscopy in identifying and treating the clival CSF rhinorrhea is emphasized. To our knowledge, this is the first report of a clival fistula secondary to a tiny intradural chordoma.
我们报告了 1 例以颅底脊索瘤为表现的微小颅内脊索瘤患者，该患者最初的症状是脑脊液（CSF）鼻漏。影像学检查和术中内镜检查均成功定位了颅底硬膜缺损和颅内肿瘤。通过经鼻内镜入路完全切除肿瘤，并修复 CSF 瘘。讨论了这种罕见情况的诊断、可能的发病机制和治疗方法。强调了内镜在识别和治疗颅底 CSF 鼻漏中的作用。据我们所知，这是首例因微小颅内脊索瘤引起的颅底瘘的报道。
