• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Binding of 125I-labeled glucagon and glucagon-stimulated accumulation of adenosine 3':5'-monophosphate in isolated intact rat hepatocytes. Evidence for receptor heterogeneity.

作者信息

Sonne O, Berg T, Christoffersen T

出版信息

J Biol Chem. 1978 May 10;253(9):3203-10.

PMID:205543
Abstract
摘要

相似文献

1
Binding of 125I-labeled glucagon and glucagon-stimulated accumulation of adenosine 3':5'-monophosphate in isolated intact rat hepatocytes. Evidence for receptor heterogeneity.
J Biol Chem. 1978 May 10;253(9):3203-10.
2
Glucagon-like peptide-1 does not have a role in hepatic carbohydrate metabolism.胰高血糖素样肽-1在肝脏碳水化合物代谢中不起作用。
Diabetologia. 1985 Dec;28(12):920-1. doi: 10.1007/BF00703137.
3
Insulin and glucagon-receptor interactions in the genetically obese Zucker rat: studies of hormone binding and glucagon-stimulated cyclic AMP levels in isolated hepatocytes.遗传性肥胖的 Zucker 大鼠中胰岛素与胰高血糖素受体的相互作用：对分离肝细胞中激素结合及胰高血糖素刺激的环磷酸腺苷水平的研究
Endocrinology. 1977 Jul;101(1):236-49. doi: 10.1210/endo-101-1-236.
4
Degradation of glucagon receptors by dispase treatment of isolated intact rat hepatocytes.通过对分离的完整大鼠肝细胞进行 dispase 处理来降解胰高血糖素受体。
Biochim Biophys Acta. 1982 Oct 11;721(2):218-22. doi: 10.1016/0167-4889(82)90071-4.
5
Receptor binding of glucagon and adenosine 3',5'-monophosphate accumulation in isolated rat fat cells.胰高血糖素的受体结合及分离的大鼠脂肪细胞中3',5'-环磷酸腺苷的积累
Biochim Biophys Acta. 1977 Sep 29;499(2):259-72. doi: 10.1016/0304-4165(77)90008-3.
6
Effects of growth hormone and glucagon on ornithine decarboxylase activity and adenosine 3',5'-monophosphate levels in isolated rat hepatocytes.
Endocrinology. 1980 Jan;106(1):125-32. doi: 10.1210/endo-106-1-125.
7
Direct evidence of a glucagon-dependent regulation of the concentration of glucagon receptors in the liver.肝脏中胰高血糖素受体浓度受胰高血糖素依赖性调节的直接证据。
Eur J Biochem. 1982 Jan;121(3):671-7. doi: 10.1111/j.1432-1033.1982.tb05838.x.
8
A quantitative analysis of glucagon binding to isolated intact neonatal and adult rat hepatocytes on the basis of two different binding models.基于两种不同的结合模型，对胰高血糖素与分离出的完整新生大鼠和成年大鼠肝细胞的结合进行定量分析。
Biochim Biophys Acta. 1982 Feb 25;714(3):448-55. doi: 10.1016/0304-4165(82)90153-2.
9
Responsiveness to glucagon by isolated rat hepatocytes controlled by the redox state of the cytosolic nicotinamide--adenine dinucleotide couple acting on adenosine 3':5'-cyclic monophosphate phosphodiesterase.分离的大鼠肝细胞对胰高血糖素的反应性受作用于腺苷3':5'-环磷酸单酯磷酸二酯酶的胞质烟酰胺-腺嘌呤二核苷酸偶联的氧化还原状态控制。
Biochem J. 1978 Dec 15;176(3):805-16. doi: 10.1042/bj1760805.
10
The effect of streptozotocin-induced diabetes on the early steps of glucagon action in isolated rat liver cells.
Diabetologia. 1980 Jul;19(1):74-80. doi: 10.1007/BF00258315.

引用本文的文献

1
Glucagon, cyclic AMP, and hepatic glucose mobilization: A half-century of uncertainty.胰高血糖素、环腺苷酸和肝糖动员：半个世纪的不确定性。
Physiol Rep. 2022 May;10(9):e15263. doi: 10.14814/phy2.15263.
2
The hepatic glucose-mobilizing effect of glucagon is not mediated by cyclic AMP most of the time.大多数情况下，胰高血糖素的肝脏葡萄糖动员作用并非由环磷酸腺苷介导。
Am J Physiol Endocrinol Metab. 2021 Oct 1;321(4):E575-E578. doi: 10.1152/ajpendo.00171.2021. Epub 2021 Jul 19.
3
Structural Mapping and Functional Characterization of Zebrafish Class B G-Protein Coupled Receptor (GPCR) with Dual Ligand Selectivity towards GLP-1 and Glucagon.
斑马鱼B类G蛋白偶联受体（GPCR）对胰高血糖素样肽-1（GLP-1）和胰高血糖素具有双重配体选择性的结构图谱与功能表征
PLoS One. 2016 Dec 8;11(12):e0167718. doi: 10.1371/journal.pone.0167718. eCollection 2016.
4
Co-transfection with protein kinase D confers phorbol-ester-mediated inhibition on glucagon-stimulated cAMP accumulation in COS cells transfected to overexpress glucagon receptors.与蛋白激酶D共转染可赋予佛波酯介导的对转染以过表达胰高血糖素受体的COS细胞中胰高血糖素刺激的环磷酸腺苷积累的抑制作用。
Biochem J. 1997 Sep 1;326 ( Pt 2)(Pt 2):545-51. doi: 10.1042/bj3260545.
5
A mnemonical or negative-co-operativity model for the activation of adenylate cyclase by a common G-protein-coupled calcitonin-gene-related neuropeptide (CGRP)/amylin receptor.一种用于常见G蛋白偶联降钙素基因相关神经肽（CGRP）/胰淀素受体激活腺苷酸环化酶的记忆性或负协同模型。
Biochem J. 1993 Jul 1;293 ( Pt 1)(Pt 1):229-36. doi: 10.1042/bj2930229.
6
Analysis of the adenylate cyclase signalling system, and alterations induced by culture with insulin, in a novel SV40-DNA-immortalized hepatocyte cell line (P9 cells).对一种新型的SV40-DNA永生化肝细胞系（P9细胞）中的腺苷酸环化酶信号系统及其在胰岛素培养诱导下的变化进行分析。
Biochem J. 1994 Jun 15;300 ( Pt 3)(Pt 3):835-42. doi: 10.1042/bj3000835.
7
Nerve growth factor receptors on PC12 cells: ligand-induced conversion from low- to high-affinity states.PC12细胞上的神经生长因子受体：配体诱导的从低亲和力状态到高亲和力状态的转变。
Proc Natl Acad Sci U S A. 1980 Aug;77(8):4751-5. doi: 10.1073/pnas.77.8.4751.
8
Amino acid transport in isolated rat hepatocytes.分离的大鼠肝细胞中的氨基酸转运
J Membr Biol. 1982;69(1):1-12. doi: 10.1007/BF01871236.
9
Dopaminergic binding sites in rat striatal slices and the action of guanyl nucleotides.大鼠纹状体切片中的多巴胺能结合位点及鸟苷酸的作用。
Naunyn Schmiedebergs Arch Pharmacol. 1984 Feb;325(2):116-23. doi: 10.1007/BF00506190.
10
Challenge of hepatocytes by glucagon triggers a rapid modulation of adenylate cyclase activity in isolated membranes.胰高血糖素对肝细胞的刺激会引发分离膜中腺苷酸环化酶活性的快速调节。
Biochem J. 1983 Jul 15;214(1):93-8. doi: 10.1042/bj2140093.