Warren Alpert School of Medicine, Brown University/Rhode Island Hospital, Providence, RI 02903, USA.
Cardiovasc Intervent Radiol. 2011 Jun;34(3):536-41. doi: 10.1007/s00270-010-9922-y. Epub 2010 Jun 17.
The design of laser fibers used for endovenous laser ablation (EVLA) in the management of lower-extremity varicose vein disease may affect treatment success. The purpose of this investigation is to report our experience using the gold-tip NeverTouch VenaCure laser fiber (AngioDynamics, Queensbury, NY) and to compare that to our experience with standard bare-tip fibers. A retrospective chart review of 363 consecutive EVLA treatments using the gold-tip laser fiber was performed. Demographic data including patient age, sex, history of previous varicose vein stripping, vein identity, laterality, treatment length, total applied energy in joules (J), use of adjuvant sclerotherapy and ambulatory phlebectomy, treatment-related complications, and treatment failure, which was defined as recanalization of any portion of the treated vein during follow-up as assessed by duplex ultrasound examination-were entered into a spreadsheet. These data were compared with a control group of 471 EVLA treatments performed with a standard bare-tip laser fiber. Data were analyzed using independent-samples Student's t test, chi-square test, and multivariate analysis. Demographic data were similar between the two groups. Treatments with the gold-tip fiber had a failure rate of 11.1%, whereas treatment with a bare-tip fiber had a failure rate of 2.3% during a similar follow-up period. This difference was highly statistically significant (p<0.0001). Multivariate analysis showed fiber type as the most significant factor associated with treatment failure. We conclude that laser fiber design has a significant effect on treatment success in the performance of EVLA.
用于治疗下肢静脉曲张疾病的静脉内激光消融术(EVLA)中使用的激光光纤的设计可能会影响治疗效果。本研究旨在报告我们使用金尖端NeverTouch VenaCure 激光光纤(AngioDynamics,Queensbury,NY)的经验,并将其与我们使用标准裸露尖端光纤的经验进行比较。对使用金尖端激光光纤进行的 363 例连续 EVLA 治疗的回顾性图表进行了分析。人口统计学数据包括患者年龄、性别、先前静脉曲张剥脱术史、静脉类型、侧别、治疗长度、焦耳(J)总应用能量、辅助硬化治疗和门诊静脉切除术的使用、与治疗相关的并发症和治疗失败,定义为在随访期间通过双功能超声检查评估治疗静脉的任何部分再通-被输入电子表格。这些数据与 471 例使用标准裸露尖端激光纤维进行的 EVLA 治疗的对照组进行了比较。使用独立样本 t 检验、卡方检验和多变量分析对数据进行了分析。两组的人口统计学数据相似。金尖端光纤治疗的失败率为 11.1%,而裸露尖端光纤治疗的失败率为 2.3%,在相似的随访期间。这种差异具有统计学意义(p<0.0001)。多变量分析显示光纤类型是与治疗失败最相关的因素。我们得出结论,激光光纤设计对 EVLA 治疗效果有显著影响。