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1470纳米激光及裸光纤用于交通静脉腔内激光消融术:可行性、安全性及闭塞率

Endovenous Laser Ablation of Perforating Veins: Feasibility, Safety, and Occlusion Rate Using a 1,470-nm Laser and Bare-Tip Fiber.

作者信息

Chehab Monzer, Dixit Purushottam, Antypas Elias, Juncaj Mare, Wong Oliver, Bischoff Michael

机构信息

Department of Diagnostic and Interventional Radiology, Oakland University William Beaumont School of Medicine, 3601 W. 13 Mile Rd., 2 Center, Royal Oak, MI 48073..

Department of Diagnostic and Interventional Radiology, Oakland University William Beaumont School of Medicine, 3601 W. 13 Mile Rd., 2 Center, Royal Oak, MI 48073.

出版信息

J Vasc Interv Radiol. 2015 Jun;26(6):871-7. doi: 10.1016/j.jvir.2015.02.014. Epub 2015 Apr 3.

Abstract

PURPOSE

To describe technical feasibility and safety of perforating vein ablation with the use of a 1,470-nm laser and bare-tip fiber in the management of chronic venous insufficiency (CVI).

MATERIALS AND METHODS

A total of 171 perforating veins were ablated in 101 limbs of 87 patients (mean age, 54.4 y; 79% female). Outcomes included sonographic occlusion of ablated perforator, subjective changes of insufficiency symptoms, incidence of procedure-related side effects (pain, hyperpigmentation), and complications (burn, infection, deep vein thrombosis, paresthesia). Correlation between perforator closure and patient symptoms was assessed by Pearson χ(2) test. Factors influencing failure of perforator closure were analyzed by analysis of variance.

RESULTS

Forty-nine perforating veins had previous great saphenous vein (GSV) interruption, 25 had previous small saphenous vein (SSV) interruption, 88 had previous GSV and SSV interruption, and 9 had competent saphenous systems. Ninety-one ablations were combined with microphlebectomy, 55 were combined with sclerotherapy, and 25 were performed alone. At 1 and 3 months' follow-up, 94% and 98% of ablated perforators were sonographically occluded, and 82% and 96% of patients noted complete symptom resolution, respectively. Complications included 5 cases of new-onset paresthesia and 1 case of nonocclusive deep vein thrombosis. Ablation failed in 10 perforators, and treatment failure showed significant correlations with higher clinical, etiology, anatomy, and physiology score (P = .002) and history of GSV/SSV interruption (P = .042).

CONCLUSIONS

Three-month closure of perforating veins is achievable by using a 1,470-nm laser and bare-tip fiber and can be safely performed alone or in combination with microphlebectomy or sclerotherapy at all stages of CVI severity.

摘要

目的

描述使用1470纳米激光和裸光纤进行穿支静脉消融治疗慢性静脉功能不全(CVI)的技术可行性和安全性。

材料与方法

对87例患者的101条肢体中的171条穿支静脉进行消融(平均年龄54.4岁;79%为女性)。结果包括消融穿支静脉的超声闭塞情况、静脉功能不全症状的主观变化、与手术相关的副作用(疼痛、色素沉着)发生率以及并发症(烧伤、感染、深静脉血栓形成、感觉异常)。通过Pearson χ²检验评估穿支静脉闭合与患者症状之间的相关性。采用方差分析分析影响穿支静脉闭合失败的因素。

结果

49条穿支静脉既往有大隐静脉(GSV)中断,25条既往有小隐静脉(SSV)中断,88条既往有GSV和SSV中断,9条隐静脉系统功能正常。91例消融联合了微静脉切除术,55例联合了硬化疗法,25例单独进行。在1个月和3个月随访时,超声检查显示分别有94%和98%的消融穿支静脉闭塞,分别有82%和96%的患者症状完全缓解。并发症包括5例新发感觉异常和1例非闭塞性深静脉血栓形成。10条穿支静脉消融失败,治疗失败与较高的临床、病因、解剖和生理学评分(P = .002)以及GSV/SSV中断病史(P = .042)显著相关。

结论

使用1470纳米激光和裸光纤可实现穿支静脉三个月的闭合,并且在CVI严重程度的各个阶段均可安全地单独进行或与微静脉切除术或硬化疗法联合进行。

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