Department of Colorectal Surgery, Worthing Hospital, Worthing, West Sussex, UK.
Colorectal Dis. 2010 Jun;12(6):515-25. doi: 10.1111/j.1463-1318.2009.01886.x.
A re-meta-analysis of available data within the published literature comparing laparoscopic rectopexy (LR) with open repair (OR).
We searched MEDLINE, EMBASE, CINAHL, PubMed and the Cochrane databases from January 1990 to October 2008. We searched the following MESH terms: 'laparoscopy', 'prolapse' and 'rectal prolapse'. We used the following text words: 'rectopexy', 'haemorrhoids', 'minimally invasive' and 'keyhole surgery'. The bibliography of selected trials and a Cochrane review was scrutinized and relevant references obtained. Selected trials were analysed to conduct a meta-analysis.
Twelve comparative studies on 688 patients qualified for the review. There were 330 patients in LR group and 358 in the OR group. LR takes longer to perform compared with OR. This difference was statistically significant [random effects model: standardized mean difference (SMD) 1.63, 95% CI (1.14-2.12), z = 6.56, P < 0.001]. There was a significant reduction in hospital stay between LR vs OR [random effects model: SMD -1.75, 95% CI (-2.45 to -1.05), z = -4.90, P < 0.001]. There was no statistical difference relating to morbidity, constipation, incontinence or mortality between the two groups.
Laparoscopic rectopexy is a safe and effective modality and is comparable to OR, however, there is still a paucity of randomized controlled trials within the literature regarding this subject. Until these trials are conducted, we would advise caution in deriving absolute conclusions.
对已发表文献中现有的可用数据进行再分析,比较腹腔镜直肠固定术(LR)与开放修复术(OR)。
我们检索了 1990 年 1 月至 2008 年 10 月期间 MEDLINE、EMBASE、CINAHL、PubMed 和 Cochrane 数据库。我们使用了以下 MESH 术语:“腹腔镜”、“脱垂”和“直肠脱垂”。我们使用了以下文本词:“直肠固定术”、“痔疮”、“微创”和“钥匙孔手术”。仔细审查了选定试验的参考文献和 Cochrane 综述,并获得了相关参考文献。分析选定的试验以进行荟萃分析。
12 项涉及 688 例患者的比较研究符合综述要求。LR 组有 330 例患者,OR 组有 358 例患者。LR 的手术时间比 OR 长。这种差异具有统计学意义[随机效应模型:标准化均数差(SMD)为 1.63,95%置信区间(1.14-2.12),z=6.56,P<0.001]。LR 组的住院时间明显短于 OR 组[随机效应模型:SMD=-1.75,95%置信区间(-2.45 至-1.05),z=-4.90,P<0.001]。两组之间的发病率、便秘、失禁或死亡率无统计学差异。
腹腔镜直肠固定术是一种安全有效的方法,与 OR 相当,然而,关于这个主题的文献中仍然缺乏随机对照试验。在这些试验进行之前,我们建议在得出绝对结论时要谨慎。