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阿尔特迈尔(Altemeier)手术和德洛姆(Delorme)手术治疗全层直肠脱垂术后复发的预测风险因素:对一家机构127例日本患者的分析

The Predictive Risk Factor of Postoperative Recurrence Following Altemeier's and Delorme's Procedures for Full-thickness Rectal Prolapse: An Analysis of 127 Japanese Patients in a Single Institution.

作者信息

Miura Yasuyuki, Funahashi Kimihiko, Kurihara Akiharu, Kagami Satoru, Suzuki Takayuki, Yoshida Kimihiko, Ushigome Mitsunori, Kaneko Tomoaki

机构信息

Department of General and Gastroenterological Surgery, Toho University Omori Medical Center, Tokyo, Japan.

出版信息

J Anus Rectum Colon. 2024 Jul 30;8(3):171-178. doi: 10.23922/jarc.2023-044. eCollection 2024.

Abstract

OBJECTIVES

We aimed to identify risk factors for postoperative recurrence (PR) after Altemeier's and Delorme's procedures for full-thickness rectal prolapse (FTRP).

METHODS

We enrolled 127 patients who underwent Altemeier's and Delorme's procedures for FTRP between April 2008 and September 2021. We divided the 127 patients into recurrence and non-recurrence groups and conducted univariate and multivariate analyses. We used six independent variables: age, body mass index (BMI), history of surgical repair for FTRP, coexistence of prolapse in other organs, poor fixation of the rectum on defecography before surgery, length of the prolapsed rectum, and type of surgical procedure (Altemeier's or Delorme's procedures).

RESULTS

PR developed in 51 (40.1%) patients during a mean follow-up period of 453 (range, 9-3616) days. Comparing the recurrence group (n=51) with the non-recurrence group (n=76), significant difference was observed regarding the coexistence of prolapse in other organs (p=0.017) in the univariate analysis. In the multivariate analysis, significant differences were observed in BMI (OR 1.18, 95% CI 1.030-1.350, p=0.020), coexistence of prolapse in other organs (OR 3.38, 95% CI 1.200-9.500, p=0.021), length of the prolapsed rectum (OR 1.030, 95% CI 1.010-1.060, p=0.015), poor fixity of the rectum on defecography (OR 0.332, 95% CI 0.129-0.852, p=0.022), and surgical procedures (OR 0.192, 95% CI 0.064-0.573, p=0.003).

CONCLUSIONS

The study suggested that increasing BMI, coexistence of prolapse in other organs, length of the prolapsed rectum, poor fixation of the rectum on defecography before surgery, and types of surgical procedure might be risk factors of PR after perineal surgery for FTRP.

摘要

目的

我们旨在确定经阿尔特迈尔手术和德洛姆手术治疗全层直肠脱垂(FTRP)后术后复发(PR)的风险因素。

方法

我们纳入了2008年4月至2021年9月期间接受阿尔特迈尔手术和德洛姆手术治疗FTRP的127例患者。我们将这127例患者分为复发组和非复发组,并进行单因素和多因素分析。我们使用了六个自变量:年龄、体重指数(BMI)、FTRP手术修复史、其他器官脱垂并存、术前排粪造影时直肠固定不良、脱垂直肠长度以及手术方式(阿尔特迈尔手术或德洛姆手术)。

结果

在平均453天(范围9 - 3616天)的随访期内,51例(40.1%)患者发生了PR。在单因素分析中,将复发组(n = 51)与非复发组(n = 76)进行比较,发现其他器官脱垂并存方面存在显著差异(p = 0.017)。在多因素分析中,BMI(OR 1.18,95%CI 1.030 - 1.350,p = 0.020)、其他器官脱垂并存(OR 3.38,95%CI 1.200 - 9.500,p = 0.021)、脱垂直肠长度(OR 1.030,95%CI 1.010 - 1.060,p = 0.015)、术前排粪造影时直肠固定不良(OR 0.332,95%CI 0.129 - 0.852,p = 0.022)以及手术方式(OR 0.192,95%CI 0.064 - 0.573,p = 0.003)方面存在显著差异。

结论

该研究表明,BMI增加、其他器官脱垂并存、脱垂直肠长度、术前排粪造影时直肠固定不良以及手术方式可能是会阴手术治疗FTRP后PR的风险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3da2/11286377/947cb8be50fc/2432-3853-8-0171-g001.jpg

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