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如何减少颈椎前路手术中喉返神经麻痹:一项前瞻性观察研究。

How to reduce recurrent laryngeal nerve palsy in anterior cervical spine surgery: a prospective observational study.

机构信息

Department of Neurosurgery, Rheinische Friedrich-Wilhelms, Universität Bonn, Bonn, Germany.

出版信息

Neurosurgery. 2010 Jul;67(1):10-5; discussion 15. doi: 10.1227/01.NEU.0000370203.26164.24.

Abstract

BACKGROUND

Recurrent laryngeal nerve palsy (RLNP) occurs as a complication during anterior cervical spine surgery. In 2005 the authors demonstrated the high incidence of asymptomatic RLNP in a right-sided approach.

OBJECTIVE

This follow-up prospective observational study was designed to test 2 options said to reduce the rate of RLNP: reduced endotracheal cuff pressure and sinistral approach.

METHODS

Two hundred forty-two patients in whom anterior cervical spine surgery was performed were examined postoperatively with indirect laryngoscopy to evaluate the status of the vocal cords. All patients had a left-sided approach but 1 group (A, 149 patients) was operated on with an additional reduction of endotracheal cuff pressure to below 20 mm Hg. In 93 patients we could not reduce the cuff pressure. This group served as a control group (B). Both groups were compared with a historic control group with a right-sided approach and no cuff pressure reduction. In cases of vocal cord malfunction a follow-up examination was done 3 months later.

RESULTS

Group A (low cuff pressure) had a total rate of persisting symptomatic and asymptomatic RLNP of 1.3% and group B had a rate of 6.5% (normal cuff pressure). Compared with the historic study (N = 120) with a right-sided approach and a total rate of persisting RLNP of 13.3% in the left-sided approach, a marked reduction to 6.5% and 1.3% with an additional reduction of cuff pressure was seen.

CONCLUSION

The left-sided approach in anterior cervical spine surgery reduces the incidence of postoperative and permanent RLNP significantly. Endotracheal cuff pressure reduction used additionally decreases the rate of RLNP even more. These results indicate that anterior cervical spine surgery should be performed with a left-sided approach and, if possible, with an additional reduction of the endotracheal cuff pressure while the retractors are inserted.

摘要

背景

喉返神经麻痹(RLNP)是颈椎前路手术的一种并发症。2005 年,作者在右侧入路中证实了无症状 RLNP 的高发生率。

目的

本随访前瞻性观察研究旨在测试两种据称可降低 RLNP 发生率的方案:降低气管内套囊压力和左侧入路。

方法

对 242 例行颈椎前路手术的患者进行术后间接喉镜检查,以评估声带状况。所有患者均采用左侧入路,但其中一组(A 组,149 例)采用附加的气管内套囊压力降低至 20mmHg 以下。在 93 例患者中,我们无法降低套囊压力。该组作为对照组(B 组)。将两组与采用右侧入路且未降低套囊压力的历史对照组进行比较。对于声带功能障碍的病例,在 3 个月后进行随访检查。

结果

A 组(低套囊压力)持续性有症状和无症状 RLNP 的总发生率为 1.3%,B 组为 6.5%(正常套囊压力)。与采用右侧入路且左侧入路持续性 RLNP 总发生率为 13.3%的历史研究(N=120)相比,明显降低至 6.5%和 1.3%,同时附加降低套囊压力。

结论

颈椎前路手术采用左侧入路可显著降低术后和永久性 RLNP 的发生率。附加降低气管内套囊压力可进一步降低 RLNP 的发生率。这些结果表明,颈椎前路手术应采用左侧入路,如果可能的话,在插入牵开器时应附加降低气管内套囊压力。

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