The distribution of the inherited Hl 1 and R 67 antigens on rabbit serum high density lipoprotein (HDL) particles.

Qualitative and quantitative analysis of the distribution of Hl 1 antigen and R 67 antigen on high density lipoprotein (HDL) particles were conducted on six rabbit sera. The Hl 1 antigen showed non-identity with A-I-containing HDL particles, and antiserum to Hl 1 did not remove A-I-containing HDL particles. The R 67 antigen showed partial identity with A-I-containing HDL particles. Antiserum to R 67 antigen removed 30--40% of A-I-containing HDL particles from the sera of animals which were heterozygous for R 67, and 65% of the A-I-containing HDL particles from the serum of one R67 homozygous animal.