Daraï Emile, Bazot Marc, Ballester Marcos
Service de gynécologie-obstétrique, hôpital Tenon (AP-HP), université Pierre-et-Marie-Curie Paris-6, 75020 Paris Cedex.
Rev Prat. 2010 May 20;60(5):603-5, 607-9.
Endometriosis is an estrogen-dependant disease that affects 10 to 15% of women of reproductive age. Its aetiology and molecular mechanisms involved have not yet been fully explored. Endometriosis is defined by the presence of endometrium-like tissue outside the uterus, primarily on the pelvic peritoneum and ovaries. The main clinical features are chronic pelvic pain, pain during intercourse, and infertility. Due to the limitations of clinical examination, additional explorations such as transvaginal sonography and magnetic resonance imaging are required to precise mapping of endometriotic lesions. Medical therapies based on progesterone and gonadotropin-releasing hormone agonists have a suspensive effect. In some cases, surgery is necessary and will be best achieved in specialized centers.
子宫内膜异位症是一种雌激素依赖性疾病，影响10%至15%的育龄妇女。其病因及相关分子机制尚未完全明确。子宫内膜异位症的定义是子宫外存在类似子宫内膜的组织，主要位于盆腔腹膜和卵巢。主要临床症状为慢性盆腔疼痛、性交痛和不孕。由于临床检查存在局限性，需要进行额外的检查，如经阴道超声检查和磁共振成像，以精确描绘子宫内膜异位症病变。基于孕激素和促性腺激素释放激素激动剂的药物治疗具有缓解作用。在某些情况下，手术是必要的，并且在专业中心进行手术效果最佳。
