Milvae R A, Duby R T, Tritschler J P, Pekala R F, Gnatek G G, Bushmich S L, Schreiber D T
Department of Animal Science, University of Connecticut, Storrs 06269-4040.
J Reprod Fertil. 1991 May;92(1):133-8. doi: 10.1530/jrf.0.0920133.
Oxytocin was administered to Dorset and Shropshire ewes in one experiment and to Dorset ewes in a further 4 experiments. In Exp. 1, concentrations of plasma progesterone and lengths of the oestrous cycle in ewes given oxytocin subcutaneously twice a day on Days 0-3, 2-5, 4-7, 6-9, 8-11, 10-13, 12-15 or 14-17 were similar to those of control ewes. In Exp. 2, intraluteal infusions of oxytocin from Day 2 to Day 9 after oestrus had no effect on concentration of progesterone, weight of CL collected on Day 9 or length of the oestrous cycle. In Exp. 3, intraluteal infusions of oxytocin on Days 10-15 after oestrus had no effect on weight of CL collected on Day 15. In Exp. 4, s.c. injections of oxytocin on Days 3-6 after oestrus had no effect on weight of CL collected on Day 9, concentrations of progesterone or length of the oestrous cycle. In Exp. 5, s.c. injections of oxytocin twice a day did not affect the maintenance and outcome of pregnancy in lactating and nonlactating ewes. Exogenous oxytocin, therefore, does not appear to affect luteal function at any stage of the ovine oestrous cycle although oxytocin has been reported by others to alter ovine CL function.
在一项实验中，向多塞特和什罗普郡母羊注射了催产素，在另外4项实验中则只对多塞特母羊注射了催产素。在实验1中，于第0 - 3天、2 - 5天、4 - 7天、6 - 9天、8 - 11天、10 - 13天、12 - 15天或14 - 17天每天皮下注射两次催产素的母羊，其血浆孕酮浓度和发情周期长度与对照母羊相似。在实验2中，发情后第2天至第9天进行黄体内注射催产素，对孕酮浓度、第9天采集的黄体重量或发情周期长度均无影响。在实验3中，发情后第10 - 15天进行黄体内注射催产素，对第15天采集的黄体重量没有影响。在实验4中，发情后第3 - 6天皮下注射催产素，对第9天采集的黄体重量、孕酮浓度或发情周期长度均无影响。在实验5中，每天皮下注射两次催产素对泌乳和非泌乳母羊的妊娠维持及结局没有影响。因此，外源性催产素似乎不会在绵羊发情周期的任何阶段影响黄体功能，尽管其他人曾报道催产素会改变绵羊黄体功能。
