Department of Ophthalmology, Istanbul Bilim University, Istanbul, Turkey.
J Ocul Pharmacol Ther. 2010 Jun;26(3):301-3. doi: 10.1089/jop.2009.0148.
The posterior reversible encephalopathy syndrome (PRES), a complex of cerebral disorders including headache, seizures, visual disturbances, is associated with a variety of conditions in which blood pressure rises acutely. Arterial hypertension can occur in systemic administration of bevacizumab. A few cases of systemic injection of bevazicumab-induced PRES have been reported. In this article, we first report on a patient who developed PRES following intravitreal bevazicumab.
后部可逆性脑病综合征(PRES)是一种包括头痛、癫痫、视觉障碍在内的脑部疾病,与多种血压急剧升高的疾病相关。贝伐单抗全身给药可导致动脉高血压。有少数贝伐单抗全身注射引起 PRES 的病例报道。本文首次报道了 1 例玻璃体腔注射贝伐单抗后发生 PRES 的患者。