Section of Dermatology, Di.S.E.M., University of Genoa, Genoa, Italy.
Contact Dermatitis. 2010 Mar;62(3):150-6. doi: 10.1111/j.1600-0536.2009.01655.x.
Clinical performance measurements often employ outcome indicators to express the extent to which health services achieve a given clinical result.
The objective of our study was to develop an outcome indicator of patch testing. We identified and measured as a possible indicator the ratio of patients with allergic and/or photo-allergic contact dermatitis clinically cured/improved as a result of identification of relevant allergens.
PATIENTS/METHODS: Patients with positive reactions considered relevant to their current dermatitis were interviewed by telephone 2 months after patch/photo-patch testing in order to assess their clinical outcome in relation to the recommended elimination of supposedly relevant allergens.
Over a 4-year period positive reactions were seen in 1397 out of 2857 tested patients. Relevance was considered current in 578 subjects, and 506 of them were interviewed. Remission/significant improvement following allergen(s) contact avoidance was reported by 431 patients, the outcome indicator (431/506) thus scoring 85.2%. Among the 75 patients who reported no improvement, 41 had not avoided contact with the offending substance(s), 17 had other persistent concomitant skin conditions, and 17 were unchanged despite elimination of the alleged relevant allergens.
The ratio of relevantly patch-test-positive patients resolved/improved after allergen avoidance is a useful patch-testing outcome indicator.
临床绩效测量通常采用结局指标来表示卫生服务在多大程度上实现了特定的临床结果。
我们研究的目的是开发一种斑贴试验的结局指标。我们确定并测量了可能的指标，即由于识别相关变应原，临床治愈/改善的变应性和/或光变应性接触性皮炎患者的比例。
患者/方法：对接受斑贴/光斑贴试验后 2 个月出现阳性反应且被认为与当前皮炎相关的患者进行电话访谈，以评估他们在推荐消除疑似相关变应原后临床结局。
在 4 年期间，2857 例接受测试的患者中有 1397 例出现阳性反应。在 578 例被认为与当前疾病相关的患者中，对其中 506 例进行了访谈。431 例患者报告在避免接触变应原后症状缓解/显著改善，该结局指标（431/506）得分为 85.2%。在 75 例报告无改善的患者中，41 例未避免接触致病物质，17 例存在其他持续性伴发皮肤病，17 例尽管消除了疑似相关变应原但病情无变化。
避免变应原后相关斑贴试验阳性患者缓解/改善的比例是一种有用的斑贴试验结局指标。
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