Nagoya University, School of Health Sciences, 1-1-20 Daiko-Minami, Higashi-ku, Nagoya 461-8673, Japan.
Clin Neurophysiol. 2010 Dec;121(12):2065-9. doi: 10.1016/j.clinph.2010.05.007. Epub 2010 Jun 20.
We investigated whether incomprehensible high-speed auditory speech stimulation was processed and interacted with visual-word discrimination processing. We hypothesised that an interaction might indicate the capacity of working memory (WM) to perform the temporal processing of auditory verbal information.
We recorded P300 for a visual-word discrimination Oddball paradigm in 14 healthy subjects. Auditory speech and reversed speech stimulation were presented at various speeds as task-irrelevant stimuli during the P300 tasks.
The P300 latency was prolonged under forward high-speed speech stimuli (× 2.5 and × 3.5) compared with the standard speed and white noise, but there was no effect of reversed speech stimuli on the P300 latency during the word-discrimination paradigm.
We considered that high-speed speech stimulation was processed without conscious comprehension and competed with verbal processing during the visual-word-discrimination task, possibly by interfering with the use of WM.
The present study shows the capacity of the brain to process high-speed verbal stimulation and the interaction with a visual-verbal task.
我们研究了难以理解的高速听觉言语刺激是否被处理并与视觉词汇辨别处理相互作用。我们假设这种相互作用可能表明工作记忆（WM）的能力能够进行听觉言语信息的时间处理。
我们在 14 名健康受试者中记录了视觉词汇辨别Oddball 范式的 P300。在 P300 任务期间，听觉言语和反转言语刺激以不同的速度作为与任务无关的刺激呈现。
与标准速度和白噪声相比，正向高速言语刺激（×2.5 和 ×3.5）下 P300 潜伏期延长，但在单词辨别范式期间，反转言语刺激对 P300 潜伏期没有影响。
我们认为高速言语刺激在没有意识理解的情况下被处理，并在视觉词汇辨别任务中与言语处理竞争，可能通过干扰 WM 的使用来实现。
本研究表明大脑处理高速言语刺激的能力以及与视觉言语任务的相互作用。
