Sugimoto Katsumi, Sasaki Kensyuu, Karaki Hirokazu, Okaya Tomohisa, Suzuki Hirofumi, Hayashi Shinniti, Yamamoto Kazuo, Yamamori Hideo, Sugano Isamu
Department of Surgery, Chibaken Saiseikai Narashino Hospital.
Gan To Kagaku Ryoho. 2010 Jun;37(6):1101-3.
We report a case of non-curatively resected esophageal cancer with no recurrence biweekly treated with postoperative docetaxel/nedaplatin combined chemotherapy. A 59-year-old woman underwent non-curative resection with esophagectomy for advanced esophageal cancer with direct invasion to the descending aorta in August, 2007. Postoperatively, she was treated biweekly with docetaxel/nedaplatin combined chemotherapy 32 times. In this period, there was no finding in the enhanced CTs, and clinically she was free from recurrence. The quality of life of this patient was also good. Thus, postoperative biweekly docetaxel/nedaplatin combined chemotherapy could be effective for advanced esophageal cancer after non-curative surgery and might be promising for long-term survival. This combined chemotherapy could be carried out on an outpatient basis, and the quality of life could also be preserved. More experience must be accumulated using this chemotherapy.
我们报告一例非根治性切除的食管癌患者，术后每两周接受多西他赛/奈达铂联合化疗，未出现复发。一名59岁女性于2007年8月因晚期食管癌直接侵犯降主动脉接受了非根治性食管切除术。术后，她每两周接受多西他赛/奈达铂联合化疗32次。在此期间，增强CT检查未发现异常，临床检查未发现复发。该患者的生活质量也良好。因此，术后每两周进行多西他赛/奈达铂联合化疗对非根治性手术后的晚期食管癌可能有效，并且可能对长期生存有帮助。这种联合化疗可以在门诊进行，同时也能维持生活质量。必须积累更多使用这种化疗方法的经验。
