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一项评估肠系膜梗死术后风险及长期预后的前瞻性研究

[A prospective study for evaluating postoperative risk and long-term prognosis of mesenteric infarct].

作者信息

Böttger T, Schäfer W, Junginger T

机构信息

Klinik und Poliklinik für Allgemein- und Abdominal-chirurgie, Johannes-Gutenberg-Universität Mainz.

出版信息

Med Klin (Munich). 1991 Apr 15;86(4):198-203, 228.

PMID:2056985
Abstract

In a prospective study on the patient material of the Surgical Clinic of the Johannes-Gutenberg-University Mainz the prognostically relevant factors in acute mesenteric vascular occlusion were investigated. From September 1, 1985 until August, 31, 1989 46 patients (24 men, 22 women) with an average age of 67.2 years were treated for an acute mesenteric vascular occlusion. Postoperatively 56.5% of the patients died. The postoperative lethality was correlated statistically significant to the period of anamnesis, the aetiology of the occlusion, the patient's age, the preoperative ASA score, and the length of the ischemically damaged bowel. The postoperative blood lactat level correlated with the outcome. Only two patients survived a second operation with a further bowel resection. One of these patients had a normal blood lactat level. The two year survival rate of the postoperative surviving patient's totalled at 70%. These results confirm the known prognostically relevant factors as well as the value of the blood lactat level in the postoperative period. They show as well, that an early second look operation depending on the intraoperative findings of the primarily operation and prior to an increase of the blood lactat level and prior to a deterioration in the patients condition is justified.

摘要

在一项针对美因茨约翰内斯 - 古腾堡大学外科诊所患者资料的前瞻性研究中,对急性肠系膜血管闭塞的预后相关因素进行了调查。从1985年9月1日至1989年8月31日,46例(24例男性,22例女性)平均年龄为67.2岁的患者接受了急性肠系膜血管闭塞治疗。术后56.5%的患者死亡。术后死亡率与病史时长、闭塞病因、患者年龄、术前ASA评分以及缺血性肠损伤长度存在统计学显著相关性。术后血乳酸水平与预后相关。仅2例患者在再次行肠切除术后存活。其中1例患者血乳酸水平正常。术后存活患者的两年生存率总计为70%。这些结果证实了已知的预后相关因素以及术后血乳酸水平的价值。它们还表明,根据初次手术的术中发现,在血乳酸水平升高之前且在患者病情恶化之前进行早期二次探查手术是合理的。

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