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[醋硝香豆素过量导致的腹直肌鞘血肿]

[Rectus sheath hematomas caused by acenocumarol overdose].

作者信息

Antal András, Kovács Zoltán, Varga József, Horváth László

机构信息

Nagyatádi Városi Kórház, Sebészeti Osztály, 7500 Nagyatád, Bajcsy-Zsilinszky u. 1.

出版信息

Magy Seb. 2010 Jun;63(3):118-20. doi: 10.1556/MaSeb.63.2010.3.3.

Abstract

Acenocumarol is widely used in long-term anticoagulant treatment. Overdose of this drug may result in suffusions in various parts of the body. In three cases, we observed suffusion in the rectus sheath, which is an unusual site of hematomas. At early stage, the lack of discoloration of the abdominal wall may lead to problems in differential diagnosis. Chronic anticoagulant treatment in a patient's history in combination with a palpable abdominal mass facilitate the correct diagnosis. In addition, high INR also makes hemorrhagic complications more likely. In simple cases, suggestive past medical history, abdominal palpation, INR and ultrasound examination can be sufficient to make a diagnosis. However, in more complicated cases, further assessment by CT is required to set up the diagnosis; while, in a further case discussed in this article, we could only establish an accurate diagnosis with laparoscopy. Decreased plasma prothrombin levels were always normalized with vitamin K.

摘要

醋硝香豆素广泛用于长期抗凝治疗。该药物过量可能导致身体各部位出现瘀斑。在三例病例中,我们观察到腹直肌鞘内出现瘀斑,这是血肿的一个不寻常部位。在早期,腹壁无变色可能会导致鉴别诊断出现问题。患者既往有慢性抗凝治疗史且可触及腹部肿块有助于正确诊断。此外,国际标准化比值(INR)升高也使出血并发症更易发生。在简单病例中,提示性的既往病史、腹部触诊、INR及超声检查足以做出诊断。然而,在更复杂的病例中,需要通过CT进一步评估以明确诊断;而在本文讨论的另一病例中,我们只能通过腹腔镜检查才能做出准确诊断。血浆凝血酶原水平降低总是通过维生素K得以恢复正常。

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