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严重急性胰腺炎中腹腔间隔室综合征的介入和手术治疗。

Interventional and surgical management of abdominal compartment syndrome in severe acute pancreatitis.

机构信息

Institute for Biomedical Research, Kau-nas University of Medicine, 50009 Kaunas, Lithuania.

出版信息

Medicina (Kaunas). 2010;46(4):249-55.

Abstract

BACKGROUND AND OBJECTIVE

Management of the abdominal compartment syndrome during severe acute pancreatitis by the open abdomen method is associated with considerable morbidity and resource utilization. Thus, the aim of this study was to evaluate the safety and efficacy of the ultrasound-guided percutaneous interventions and/or minimally invasive surgery in the treatment of abdominal compartment syndrome.

MATERIAL AND METHODS

Forty-four patients with severe acute pancreatitis were enrolled into a prospective study and treated according to the standard management protocol. Interventional and/or surgical management of abdominal compartment syndrome was employed in 6 (13.6%) cases. In the context of this study, we assessed the feasibility and effectiveness of subcutaneous fasciotomy of the anterior m. rectus abdominis sheath, as well as the role of ultrasound-guided drainage of intra-abdominal and peripancreatic fluid collections in the management of abdominal compartment syndrome.

RESULTS

Subcutaneous fasciotomy of the anterior m. rectus sheath and ultrasound-guided drainage of intra-abdominal and peripancreatic fluid collections seem to be safe (minor risk of bleeding or infection, closed abdomen, and easy care for the patient) and effective (resulted in a sustained decrease of intra-abdominal pressure to 13-16 mm Hg and regression of organ failures after intervention). Subcutaneous anterior m. rectus fasciotomy may appear to be beneficial in case of refractory abdominal compartment syndrome avoiding morbidity associated with the open abdomen technique.

CONCLUSIONS

Both the subcutaneous fasciotomy and ultrasound-guided drainage of intra-abdominal and/or peripancreatic fluid collections seem to be safe and effective alternatives in the management of abdominal compartment syndrome; however, prospective studies are needed to further evaluate their clinical role.

摘要

背景与目的

采用开放性腹部方法治疗重症急性胰腺炎并发腹腔间隔室综合征会导致较高的发病率和资源利用。因此,本研究旨在评估超声引导下经皮介入和/或微创手术治疗腹腔间隔室综合征的安全性和疗效。

材料与方法

44 例重症急性胰腺炎患者纳入前瞻性研究,并根据标准治疗方案进行治疗。6 例(13.6%)采用介入和/或手术治疗腹腔间隔室综合征。在本研究中,我们评估了腹直肌前鞘皮下筋膜切开术的可行性和有效性,以及超声引导下引流腹腔和胰周积液在腹腔间隔室综合征治疗中的作用。

结果

腹直肌前鞘皮下筋膜切开术和超声引导下引流腹腔和胰周积液似乎是安全的(出血或感染风险低,可关闭腹部,便于患者护理)和有效的(可将腹腔内压力持续降至 13-16mmHg,并在干预后器官衰竭得到缓解)。在出现难治性腹腔间隔室综合征时,皮下前腹直肌筋膜切开术可能比开放性腹部技术更有益,可避免与该技术相关的发病率。

结论

皮下筋膜切开术和超声引导下引流腹腔和/或胰周积液似乎是治疗腹腔间隔室综合征的安全有效替代方法;然而,需要进一步开展前瞻性研究来评估其临床作用。

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