Feng Ye-Chen, Wang Min, Zhu Feng, Qin Ren-Yi
Ye-Chen Feng, Min Wang, Feng Zhu, Ren-Yi Qin, Department of Biliary-Pancreatic Surgery, Affiliated Tongji Hospital, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China.
World J Gastroenterol. 2014 Nov 21;20(43):16138-45. doi: 10.3748/wjg.v20.i43.16138.
Acute pancreatitis (AP) is an inflammatory disease of the pancreas which involves the pancreas and surrounding tissue, and systemic inflammation with a characteristic systemic increase of vascular permeability and increased risk of multiple organ dysfunction. Currently, the pathogenesis of AP is fuzzy, and the diagnosis and treatment need to be standardized. Nevertheless, increased knowledge of AP may achieve more thorough understanding of the pathogenesis. The use of further advanced diagnostic tools and superior treatment, potentially will help clinicians to manage AP at an appropriate stage. However, in view of the multi factorial disease and the complex clinical manifestations, the management of patients with AP is also remaining areas for improvement.
急性胰腺炎(AP)是一种胰腺的炎症性疾病,累及胰腺及其周围组织,并伴有全身性炎症,其特征为血管通透性系统性增加以及多器官功能障碍风险升高。目前,AP的发病机制尚不明确,诊断和治疗需要规范化。然而,对AP了解的增加可能会使我们对其发病机制有更深入的认识。使用更先进的诊断工具和更优的治疗方法,可能会帮助临床医生在适当阶段对AP进行管理。然而,鉴于这种多因素疾病以及复杂的临床表现,AP患者的管理仍有改进空间。