随机临床试验研究荷包缝合与传统缝合在肠造口伤口愈合短期结局方面的差异。
Randomized clinical trial of short-term outcomes following purse-string versus conventional closure of ileostomy wounds.
机构信息
Department of Colorectal Surgery, John Hunter Hospital, New South Wales, Australia.
出版信息
Br J Surg. 2010 Oct;97(10):1511-7. doi: 10.1002/bjs.7151.
BACKGROUND
Ileostomy closure is an operation with an underappreciated morbidity, including surgical-site infection, small bowel obstruction and anastomotic leakage. Surgical-site infections, in particular, are a frequent occurrence following closure of contaminated wounds. This randomized controlled trial compared a purse-string closure technique with conventional linear closure.
METHODS
Sixty-one patients were randomized to conventional or purse-string closure of ileostomy wounds. The primary endpoint was the incidence of surgical-site infection, including infections requiring hospital or community treatment.
RESULTS
Purse-string closure resulted in fewer surgical-site infections than conventional closure: two of 30 versus 12 of 31 respectively (P = 0.005).
CONCLUSION
The purse-string method results in a clinically relevant reduction in surgical-site infections after ileostomy closure.
REGISTRATION NUMBER
ACTRN12609000021279 (Australian New Zealand Clinical Trials Registry: http://www.anzctr.org.au/).
背景
回肠造口关闭术是一种发病率被低估的手术，包括手术部位感染、小肠梗阻和吻合口漏。特别是手术后部位感染，是污染伤口关闭后的常见并发症。本随机对照试验比较了荷包缝合技术与传统线性缝合。
方法
61 例患者随机分为传统或荷包缝合回肠造口伤口。主要终点是手术部位感染的发生率，包括需要医院或社区治疗的感染。
结果
荷包缝合组的手术部位感染发生率低于传统缝合组：分别为 2/30 例和 12/31 例（P=0.005）。
结论
荷包缝合法可显著降低回肠造口关闭术后的手术部位感染发生率。
注册号
ACTRN12609000021279（澳大利亚新西兰临床试验注册中心：http://www.anzctr.org.au/）。
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