电针联合穴位注射A型肉毒毒素治疗脊髓损伤后肌肉痉挛的临床研究

[Clinical research of electroacupuncture combined with acupoint-injection of botulinum toxin A in treating the muscle spasticity by spinal cord injury].

作者信息

Xing Shi-Tong, Wang Dan, Wen Xiao-Hong, Wu Zhong-Qing, Sun Qi, Zhang Dong-Wei, Cheng Yi, Yan Dong, Yu Fei

机构信息

Department of Orthopaedics, the 1st People's Hospital of Huzhou,Huzhou 313000, Zhejiang, China.

出版信息

Zhongguo Gu Shang. 2010 May;23(5):350-3.

PMID:20575288

Abstract

OBJECTIVE

To explore clinical safety and efficiency of electroacupuncture combined with acupoint-injection of botulinum toxin A for the treatment of muscle spasticity by spinal cord injury.

METHODS

Thirty-eight patients with muscle spasticity by spinal cord injury were treated from December 2006 to December 2009 including 26 males and 12 females, with an average age of 45.4 years old ranging from 21 to 68 years. The patients were randomly divided into 3 groups according to admission time, 13 patients in group A were treated with electroacupuncture combined with acupoint-injection of botulinum toxin A, and 13 patients in group B were treated with acupoint-injection botulinum toxin A and 12 patients in group C were treated with electroacupuncture. After 6 months these patients were evaluated by improved muscle Ashworth scoring (MAS) and clinical spasticity index (SCI).

RESULTS

Thirty-eight patients were followed-up at 6 months after the treatment. The result showed that the MAS scores of group A, B, C before treatment were (3.10 +/- 0.14), (3.20 +/- 0.17), (3.10 +/- 0.16) respectively and the CSI scores were (14.10 +/- 0.14), (14.30 +/- 0.11), (14.20 +/- 0.12) respectively; there were no statistical different among the three groups (P > 0.05). After 6 months of treatment, the MAS scores were (1.10 +/- 0.16), (2.10 +/- 0.13), (2.00 +/- 0.14) respectively and the CSI scores were (9.10 +/- 0.11), (12.10 +/- 0.14), (13.10 +/- 0.12) respectively. The MAS scores and CSI scores of group A were better than the other two groups (P < 0.05).

CONCLUSION

The combination of Chinese hydropower needles and acupoints with BTX-A injection can achieve a comprehensive treatment and reduce pain and improve life quality quickly. The electroacupuncture combined with acupoint-inject botulinum toxin A is a noval safe and effective technique for the treatment of muscle spasticity by spinal cord injury.

摘要

目的

探讨电针联合穴位注射A型肉毒毒素治疗脊髓损伤后肌肉痉挛的临床安全性及有效性。

方法

选取2006年12月至2009年12月收治的38例脊髓损伤后肌肉痉挛患者，其中男26例，女12例，平均年龄45.4岁，年龄范围21～68岁。根据入院时间将患者随机分为3组，A组13例采用电针联合穴位注射A型肉毒毒素治疗，B组13例采用穴位注射A型肉毒毒素治疗，C组12例采用电针治疗。治疗6个月后采用改良的肌肉Ashworth评分（MAS）及临床痉挛指数（SCI）进行疗效评价。

结果

38例患者均获6个月随访。结果显示，治疗前A、B、C组MAS评分分别为（3.10±0.14）、（3.20±0.17）、（3.10±0.16），SCI评分分别为（14.10±0.14）、（14.30±0.11）、（14.20±0.12），3组间比较差异无统计学意义（P＞0.05）。治疗6个月后，A、B、C组MAS评分分别为（1.10±0.16）、（2.10±0.13）、（2.00±0.14），SCI评分分别为（9.10±0.11）、（12.10±0.14）、（13.10±0.12）。A组MAS评分及SCI评分均优于其他两组（P＜0.05）。