Barozzi L, Pavlica P, Sabattini A, Losinno F, Dondi M, De Fabritiis A, Amato A, Zuccalà A
Servizio di Radiologia, Ospedale Policlinico S. Orsola-Malpighi, Bologna.
Radiol Med. 1991 May;81(5):642-9.
Doppler US was employed to examine 46 patients with suspected renovascular hypertension (RVI) to detect stenosis/occlusion of the renal artery. In 25 cases duplex-Doppler technique was used, in 19 color-Doppler US, and 2 patients were examined with both methods. Doppler US was always performed before angiography which was considered as the reference gold standard. Using duplex-Doppler US, the diagnosis of renal artery stenosis was based on qualitative (spectral analysis of the waveform and absence of flow signal in cases of renal artery occlusion), and semiquantitative parameters (resistive index). Diagnostic accuracy of duplex US--which was compared with that of angiography--was 83%, its sensitivity was 91.6%, and specificity was 85%. With color-Doppler, two additional quantitative parameters were used (peak systolic frequency shift at the stenosis and stenosis index). In this group of patients sensitivity was 70%, specificity was 100%, and accuracy 85%. The good diagnostic yield of the method is counter-balanced by some limitations--e.g., operator dependence and long examination time (30-40 minutes, especially with duplex US). In the authors' opinion, Doppler technique can be used in the diagnosis of RVI, even though further study is necessary to exactly define diagnostic parameters, and to verify reproducibility and both inter- and intra-observer repeatibility. Technological progress may in the future reduce both difficulty and time of the examination.
采用多普勒超声检查46例疑似肾血管性高血压(RVI)患者,以检测肾动脉狭窄/闭塞情况。25例采用双功多普勒技术,19例采用彩色多普勒超声,2例同时接受了两种方法的检查。多普勒超声检查均在血管造影之前进行,血管造影被视为参考金标准。使用双功多普勒超声时,肾动脉狭窄的诊断基于定性(波形频谱分析以及肾动脉闭塞时无血流信号)和半定量参数(阻力指数)。双功超声与血管造影相比的诊断准确性为83%,敏感性为91.6%,特异性为85%。彩色多普勒超声使用了另外两个定量参数(狭窄处的收缩期峰值频移和狭窄指数)。在这组患者中,敏感性为70%,特异性为100%,准确性为85%。该方法良好的诊断效果被一些局限性所抵消,例如,依赖操作人员且检查时间长(30 - 40分钟,双功超声检查时尤其如此)。作者认为,多普勒技术可用于RVI的诊断,尽管需要进一步研究以准确界定诊断参数,并验证其可重复性以及观察者间和观察者内的重复性。未来技术进步可能会减少检查的难度和时间。