Ugolotti U, Larini P, Mandrioli R, Miselli A, Villani L G, Japichino G G, Azzarone M
II Servizio di Radiologia, Ospedale Regionale, Parma.
Radiol Med. 1991 May;81(5):691-4.
From January to November 1989, 31 iliac and femoro-popliteal atherosclerotic lesions were treated in 29 patients (age range: 33-80 years) by means of percutaneous laser-assisted angioplasty. The lesions were 6 iliac tubular stenoses, 6 iliac occlusions and 19 femoro-popliteal occlusions, 2-20 cm long. The laser equipment employed was in 10 cases a Cardiolase 4000 Nd:YAG "hot tip" unit, and in 21 cases a Nd:YAG "sapphire contact probe" unit. Initial success was achieved in 23/31 lesions (74%); the follow-up, by clinical examination, Doppler US, and ankle-arm pressure index performed every 4th month, showed 1-year actuarial patency of 80% for femoro-popliteal occlusion and 100% for iliac lesion, with 87% cumulative patency. Overall complication rate was 22.5%. There were 6 local complications, 4 of which were hematomas at the arterial puncture site, and 2 were performation of the superficial femoral artery, all without any clinical sequelae; one patient developed rethrombosis within 72 hours from treatment, which needed amputation after an emergency bypass. Our preliminary results show no significant improvement when compared with conventional balloon angioplasty results both in immediate success rate and in short-to-midterm patency; furthermore, laser therapy was burdened by a higher complication rate. We believe that laser angioplasty should be employed only in arterial occlusion uncrossable with angiographic guidance alone.
1989年1月至11月,采用经皮激光辅助血管成形术治疗了29例患者(年龄范围:33 - 80岁)的31处髂动脉和股腘动脉粥样硬化病变。病变包括6处髂动脉管状狭窄、6处髂动脉闭塞和19处股腘动脉闭塞,长度为2 - 20厘米。所使用的激光设备,10例为Cardiolase 4000 Nd:YAG“热尖端”装置,21例为Nd:YAG“蓝宝石接触探头”装置。23/31处病变(74%)获得初步成功;通过临床检查、多普勒超声以及每4个月进行的踝臂压力指数进行随访,结果显示股腘动脉闭塞1年实际通畅率为80%,髂动脉病变为100%,累积通畅率为87%。总体并发症发生率为22.5%。有6例局部并发症,其中4例为动脉穿刺部位血肿,2例为股浅动脉穿孔,均无任何临床后遗症;1例患者在治疗后72小时内发生再血栓形成,紧急搭桥术后需要截肢。我们的初步结果表明,与传统球囊血管成形术相比,在即刻成功率和短期至中期通畅率方面均无显著改善;此外,激光治疗的并发症发生率更高。我们认为,激光血管成形术仅应在仅靠血管造影引导无法穿过的动脉闭塞中使用。